Journal ArticleDOI
Brain tissue reaction to some chronically implanted metals
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The toxicity of certain metals was evaluated histologically following chronic implantation for 2 months in the brains of cats and all but silver were found to be nontoxic.Abstract:
✓ The toxicity of certain metals, namely, platinum, platinum-8% tungsten, platinum-10% rhodium, platinum-10% iridium, platinum-10% nickel, platinized platinum, a gold-nickel-chromium alloy, a gold-palladium-rhodium alloy, a chromium-nickel-molybdenum alloy (Vitallium), stainless steel, silver, rhenium, and gold, was evaluated histologically following chronic implantation for 2 months in the brains of cats. Of the above metals, all but silver were found to be nontoxic. Boron was also evaluated and found to be nontoxic.read more
Citations
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Transient third nerve palsy after electrometallicthrombosis of carotid cavernous fistulae.
TL;DR: Three patients had oculomotor nerve palsy as a complication of the treatment of carotid cavernous fistulae by electrometallicthrombosis of the cavernous sinus, and in two, third nerve function returned without misdirection in two months or less.
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Fabrication and characterization of nonplanar microelectrode array circuits for use in arthroscopic diagnosis of cartilage diseases
TL;DR: Indentation measurements were performed on articular cartilage in vitro showing streaming potentials that indicate electrode-tissue contact times and generation of streaming potentialed signals generated during indentation of articular Cartilage.
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In Vivo Measurements With Robust Silicon-Based Multielectrode Arrays With Extreme Shaft Lengths
Gergely Márton,Zoltán Fekete,Richárd Fiáth,Péter Baracskay,István Ulbert,Gábor Juhász,Gábor Battistig,A. Pongrácz +7 more
TL;DR: In vivo measurements on rats indicate good mechanical stability, robust implantation, and targeting capability of extreme-long Si-based neural microelectrode arrays.
Book ChapterDOI
Vascular Clips: An Historic and Biomechanical Perspective
Manuel Dujovny,Nir Kossovsky,Ram Kossowsky,Debra Nelson,Norman Wackenhut,Alfred Perlin,Ranjit K. Laha +6 more
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Biological and hepatotoxic effects of palladium. An overview on experimental investigations and personal studies.
TL;DR: The retention, tissue distribution, excretion and placental transfer of Pd were determined by several authors following different administration routes in animal experiments and suggest that Pd may interfere with energy metabolism, acidlbase and electrolyte eqUilibria.
References
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Punctures of the brain: the factors concerned in gliosis and in cicatricial contraction
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Histopathological changes produced by implanted electrodes in cat brains; comparison with histopathological changes in human and experimental puncture wounds.
TL;DR: A review of the literature has failed to reveal a detailed chronological study of the finer microscopic changes in the central nervous system that take place consequent to implanted electrodes, and the neurophysiological literature contains a paucity of detailed histopathological examinations of sacrificed experimental animals.
Journal ArticleDOI
Evaluation of permanent implantation of electrodes within the brain
TL;DR: Conclusions 6, 7, and 8 indicate that the presence of electrodes disturbs the brain activity very little, or at least, that the experimental conditions do not change during the period of observation.