Journal ArticleDOI
Brain tissue reaction to some chronically implanted metals
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TLDR
The toxicity of certain metals was evaluated histologically following chronic implantation for 2 months in the brains of cats and all but silver were found to be nontoxic.Abstract:
✓ The toxicity of certain metals, namely, platinum, platinum-8% tungsten, platinum-10% rhodium, platinum-10% iridium, platinum-10% nickel, platinized platinum, a gold-nickel-chromium alloy, a gold-palladium-rhodium alloy, a chromium-nickel-molybdenum alloy (Vitallium), stainless steel, silver, rhenium, and gold, was evaluated histologically following chronic implantation for 2 months in the brains of cats. Of the above metals, all but silver were found to be nontoxic. Boron was also evaluated and found to be nontoxic.read more
Citations
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Journal ArticleDOI
In vivo potentiostatic studies at the electrode tissue interface: filter properties of the monophasic action potential (Ag/AgCl) electrode in living rat heart.
Howard A. Chou,Marc Ovadia,Marc Ovadia,Marc Ovadia,Michael Moskowitz,Daniel H. Zavitz,Daniel H. Zavitz +6 more
TL;DR: While the MAP electrode and model Ag/AgCl electrodes are high‐pass filters with robust transfer functions for high frequency signals in the living heart, the attenuation of signals in a frequency range relevant to in vivo physiological recording imparts extreme attenuation that may distort physiological signals unpredictably.
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Spinal stimulator peri-electrode masses: case report
TL;DR: A case of delayed spastic quadriparesis caused by a peri-electrode mass following the implantation of a minimally invasive percutaneous spinal cord stimulator (SCS).
Journal ArticleDOI
Histological change in permanently clipped or ligated cerebral arterial wall. Part I. An experimental study in dogs.
K. Ebina,T. Iwabuchi,S. Suzuki +2 more
TL;DR: In this article, the effect of permanent clipping or ligation on the intracranial arteries of 38 operation dogs and 7 control dogs was studied by light microscopy, and the results showed that the degree of necrosis correlated with the duration of clipping in the cases treated with a spring type clip, and was influenced more by the closing strength at the time of application in cases with non-spring type clips and ligation.
Book ChapterDOI
The Electrode – Materials and Configurations
TL;DR: In this article, the authors explain how selecting the correct electrode material, electrode shape, configuration and stimulation paradigm for neuromodulation involves the understanding of a large number of physical, chemical and biologic phenomena associated with electrical stimulation.
Journal ArticleDOI
The changes of serum zinc, copper, and selenium levels in epileptic patients: a systematic review and meta-analysis.
Wanying Jia,Yang Song,Lei Yang,Jingjing Kong,Tomasz Boczek,Zhenwei He,Yuting Wang,Xiaohong Zhang,Huiyuan Hu,Dongxue Shao,Hong Tang,Liguang Xia,Xiaoxue Xu,Feng Guo +13 more
TL;DR: A meta-analysis of the changes in serum Zn, Cu, and Se levels in human samples of healthy controls, epileptic patients, and patients treated with VPA provides a theoretical basis for the combined use of other drugs that affect the intake and absorption of trace elements and VPA.
References
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Punctures of the brain: the factors concerned in gliosis and in cicatricial contraction
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TL;DR: A review of the literature has failed to reveal a detailed chronological study of the finer microscopic changes in the central nervous system that take place consequent to implanted electrodes, and the neurophysiological literature contains a paucity of detailed histopathological examinations of sacrificed experimental animals.
Journal ArticleDOI
Evaluation of permanent implantation of electrodes within the brain
TL;DR: Conclusions 6, 7, and 8 indicate that the presence of electrodes disturbs the brain activity very little, or at least, that the experimental conditions do not change during the period of observation.