Catheter-Induced Errors in Pressure Measurements in Vessels: An In-Vitro and Numerical Study
Adelaide de Vecchi,Rachel E. Clough,Nicholas Gaddum,Marcel C. M. Rutten,Pablo Lamata,Tobias Schaeffter,David Nordsletten,Nicolas P. Smith +7 more
TLDR
Catheter geometry produces significant measurement bias in both the peak pressure and the waveform shape even with radius ratios considered acceptable in clinical practice, showing that the wire allows for more accurate pressure quantification, in agreement with the numerical model without a catheter.Abstract:
Accurate measurement of blood pressure is important because it is a biomarker for cardiovascular disease. Diagnostic catheterization is routinely used for pressure acquisition in vessels despite being subject to significant measurement errors. To investigate these errors, this study compares pressure measurement using two different techniques in vitro and numerical simulations. Pressure was acquired in a pulsatile flow phantom using a 6F fluid-filled catheter and a 0.014′′ pressure wire, which is considered the current gold standard. Numerical simulations of the experimental set-up with and without a catheter were also performed. Despite the low catheter-to-vessel radius ratio, the catheter traces showed a 24% peak systolic pressure overestimation compared to the wire. The numerical models replicated this difference and indicated the cause for overestimation was the increased flow resistance due to the presence of the catheter. Further, the higher frequency pressure oscillations observed in the wire and numerical data were absent in the catheter, resulting in an overestimation of the pulse wave velocity with the latter modality. These results show that catheter geometry produces significant measurement bias in both the peak pressure and the waveform shape even with radius ratios considered acceptable in clinical practice. The wire allows for more accurate pressure quantification, in agreement with the numerical model without a catheter.read more
Citations
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Beyond Bernoulli: Improving the Accuracy and Precision of Noninvasive Estimation of Peak Pressure Drops
Fabrizio Donati,Saul G. Myerson,Malenka M. Bissell,Nicolas P. Smith,Stefan Neubauer,Mark J. Monaghan,David Nordsletten,Pablo Lamata +7 more
TL;DR: A corrected formulation that accounts for the cross-sectional profile of the blood flow is proposed and adapted to both cardiovascular magnetic resonance and echocardiographic data.
Journal ArticleDOI
Non-invasive pressure difference estimation from PC-MRI using the work-energy equation.
Fabrizio Donati,C. Alberto Figueroa,Nicolas P. Smith,Nicolas P. Smith,Pablo Lamata,Pablo Lamata,David Nordsletten +6 more
TL;DR: A novel semi-automatic method for the estimation of pressure differences in cardiovascular compartments from dense velocity fields (4D flow MRI data) that relies on the work-energy principle, and removes the need for second order spatial derivatives.
Journal ArticleDOI
Beyond BernoulliCLINICAL PERSPECTIVE
Fabrizio Donati,Saul G. Myerson,Malenka M. Bissell,Nicolas P. Smith,Stefan Neubauer,Mark J. Monaghan,David Nordsletten,Pablo Lamata +7 more
TL;DR: In this paper, the authors used the Bernoulli principle to estimate the peak pressure drop at the aortic valve using 3-dimensional cardiovascular magnetic resonance flow data in 32 subjects.
Journal ArticleDOI
Evaluation of 4D flow MRI-based non-invasive pressure assessment in aortic coarctations.
Simone Saitta,Selene Pirola,Filippo Piatti,Emiliano Votta,Federico Lucherini,Francesca Romana Pluchinotta,Mario Carminati,Massimo Lombardi,Christian Geppert,Federica Cuomo,Carlos Alberto Figueroa,Xiao Yun Xu,Alberto Redaelli +12 more
TL;DR: Important validation aspects of non-invasive pressure difference estimation based on 4D flow MRI are considered, showing the potential of this technology to be more broadly applied to the clinical practice.
Journal ArticleDOI
Estimation of Cardiovascular Relative Pressure Using Virtual Work-Energy.
David Marlevi,David Marlevi,Bram Ruijsink,Bram Ruijsink,Maximilian Balmus,Desmond Dillon-Murphy,Daniel Fovargue,Kuberan Pushparajah,Kuberan Pushparajah,Cristóbal Bertoglio,Cristóbal Bertoglio,Massimiliano Colarieti-Tosti,Massimiliano Colarieti-Tosti,Matilda Larsson,Pablo Lamata,C. Alberto Figueroa,C. Alberto Figueroa,Reza Razavi,Reza Razavi,David Nordsletten +19 more
TL;DR: This work introduces a non-invasive method that enables arbitrary interrogation of relative pressures throughout an imaged vascular structure, leveraging modern phase contrast magnetic resonance imaging, the virtual work-energy equations, and a virtual field to provide robust and accurate estimates.
References
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Journal ArticleDOI
Expert consensus document on arterial stiffness: methodological issues and clinical applications
Stéphane Laurent,John R. Cockcroft,Luc M. Van Bortel,Pierre Boutouyrie,Cristina Giannattasio,Daniel Hayoz,Bruno Pannier,Charalambos Vlachopoulos,Ian B. Wilkinson,Harry A.J. Struijker-Boudier +9 more
TL;DR: This paper summarizes the proceedings of several meetings of the European Network for Non-invasive Investigation of Large Arteries and is aimed at providing an updated and practical overview of the most relevant methodological aspects and clinical applications in this area.
Journal Article
Expert consensus document on arterial stiffness : methodological issues and clinical applications. Commentary
Michael F. O'Rourke,Stanley S. Franklin,Stéphane Laurent,John R. Cockcroft,Luc M. Van Bortel,Pierre Boutouyrie,Cristina Giannattasio,Daniel Hayoz,Bruno Pannier,Charalambos Vlachopoulos,Ian B. Wilkinson,Harry A.J. Struijker-Boudier +11 more
TL;DR: In this paper, the authors summarized the proceedings of several meetings of the European Network for Non-invasive Investigation of Large Arteries and aimed at providing an updated and practical overview of the most relevant methodological aspects and clinical applications in this area.
Journal ArticleDOI
Noninvasive determination of age-related changes in the human arterial pulse.
TL;DR: Changes in peak pressure in the central (carotid) artery show increasing cardiac afterload with increasing age in a normal population; this can account for the cardiac hypertrophy that occurs with advancing age (even as other organs atrophy) and the predisposition to cardiac failure in the elderly.
Journal ArticleDOI
Systolic Blood Pressure, Arterial Rigidity, and Risk of Stroke: The Framingham Study
William B. Kannel,Philip A. Wolf,Daniel L. McGee,Thomas R. Dawber,Patricia M. McNamara,William P. Castelli +5 more
TL;DR: It would appear that isolated systolic hypertension predisposes to stroke independent of arterial rigidity, and diastolic pressure adds little to risk assessment and in men, in this subgroup, appears unrelated to stroke incidence.
Journal ArticleDOI
Influence of preoperative pulmonary artery pressure on mortality after heart transplantation: testing of potential reversibility of pulmonary hypertension with nitroprusside is useful in defining a high risk group.
TL;DR: Patients with pulmonary hypertension at risk of developing fatal right heart failure after heart transplantation are screened by measuring rest right heart pressures and the response to nitroprusside, and the influence of pretransplantation right heart catheterization data on outcome after transplantation was analyzed.