Changes in plasma very low density and low density lipoprotein content, composition, and size after a fatty meal in normo- and hypertriglyceridemic man.
T G Redgrave,L A Carlson +1 more
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TLDR
Four subfractions of plasma VLDL characterized by decreasing Sf value and LDL were isolated by density gradient preparative ultracentrifugation from normotriglyceridemic and hypertriglyceridemia subjects in the fasting state and after a fatty meal to show that the hyperlipidemia of type IV subjects was accounted for by an increase in total numbers of VLDl and a shift in the distribution of V LDL towards particles of larger diameter.About:
This article is published in Journal of Lipid Research.The article was published on 1979-02-01 and is currently open access. It has received 273 citations till now. The article focuses on the topics: Very low-density lipoprotein & Chylomicron remnant.read more
Citations
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Triglycerides and Cardiovascular Disease A Scientific Statement From the American Heart Association
Michael Miller,Neil J. Stone,Christie M. Ballantyne,Vera Bittner,Michael H. Criqui,Henry N. Ginsberg,Anne C. Goldberg,William James Howard,Marc S. Jacobson,Penny M. Kris-Etherton,Terry A. Lennie,Moshe Levi,Theodore Mazzone,Subramanian Pennathur +13 more
TL;DR: The role of triglyceride-rich lipoproteins (TRLs) in the evaluation and management of CVD risk was discussed in this article, where the authors highlighted approaches aimed at minimizing the adverse public health-related consequences associated with hypertriglyceridemic states.
Triglycerides and Cardiovascular Disease : A Scientific Statement From the
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Pravastatin Treatment Increases Collagen Content and Decreases Lipid Content, Inflammation, Metalloproteinases, and Cell Death in Human Carotid Plaques Implications for Plaque Stabilization
Milita Crisby,Gunilla Nordin-Fredriksson,Prediman K. Shah,Juliana Yano,Jenny Zhu,Jan Nilsson +5 more
TL;DR: Pravastatin decreased lipids, lipid oxidation, inflammation, MMP-2, and cell death and increased TIMP-1 and collagen content in human carotid plaques, confirming its plaque-stabilizing effect in humans.
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Lipoprotein particle analysis by nuclear magnetic resonance spectroscopy.
TL;DR: Direct assessment of lipoprotein particle numbers us now possible through nuclear magnetic resonance spectroscopic analysis.
Journal ArticleDOI
Postprandial lipoproteins and progression of coronary atherosclerosis
Fredrik Karpe,George Steiner,George Steiner,Kristine D. Uffelman,Thomas Olivecrona,Anders Hamsten +5 more
TL;DR: The data suggest that small chylomicron remnants are implicated in the progression of coronary artery disease.
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Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
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Phosphorus Assay in Column Chromatography
TL;DR: If the highest accuracy was not required, the following manipulations simplified and speeded multiple total phosphorus determinations on the eluates from column chromatographic separations.
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The plasma lecithin:cholesterol acyltransferase reaction
TL;DR: Several indications exist that the acyltransferase reaction is the major source of plasma esterified cholesterol in man, and one possibility is that it plays a role in the transport of cholesterol from peripheral tissues to the liver.
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Electrophoretic separation of plasma lipoproteins in agarose gel
TL;DR: The clearcut separation of lipoproteins by this method will facilitate the classification of hyperlipoproteinemias and improve quantitative estimates oflipoprotein distribution.
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Separation of plasma lipoproteins by density-gradient ultracentrifugation.
TL;DR: The method employs a discontinuous salt gradient and separates VLDL, LDL, and HDL as verified by cellulose acetate- and immuno-electrophoresis and offers some advantages for research applications.