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Childhood Obesity in Developing Countries: Epidemiology, Determinants, and Prevention

TLDR
Therapeutic lifestyle changes and maintenance of regular physical activity through parental initiative and social support interventions are the most important strategies in managing childhood obesity in developing countries.
Abstract
Rapidly changing dietary practices and a sedentary lifestyle have led to increasing prevalence of childhood obesity (5-19 yr) in developing countries recently: 41.8% in Mexico, 22.1% in Brazil, 22.0% in India, and 19.3% in Argentina. Moreover, secular trends indicate increasing prevalence rates in these countries: 4.1 to 13.9% in Brazil during 1974-1997, 12.2 to 15.6% in Thailand during 1991-1993, and 9.8 to 11.7% in India during 2006-2009. Important determinants of childhood obesity include high socioeconomic status, residence in metropolitan cities, female gender, unawareness and false beliefs about nutrition, marketing by transnational food companies, increasing academic stress, and poor facilities for physical activity. Childhood obesity has been associated with type 2 diabetes mellitus, the early-onset metabolic syndrome, subclinical inflammation, dyslipidemia, coronary artery diseases, and adulthood obesity. Therapeutic lifestyle changes and maintenance of regular physical activity through parental initiative and social support interventions are the most important strategies in managing childhood obesity. Also, high-risk screening and effective health educational programs are urgently needed in developing countries.

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Childhood predictors of adult obesity: a systematic review.

TL;DR: This paper found a strong consistent relationship between low socioeconomic status (SES) in early life and increased fatness in adulthood, but in studies which attempted to address potential confounding by gestational age, parental fatness, or social group, the relationship was less consistent.
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Differences in gut microbiota composition between obese and lean children: a cross-sectional study

TL;DR: The authors' findings corroborate a significant difference in the gut microbiota composition of important bacterial species between obese and lean children and could offer a new approach to manage childhood obesity and associated disorders.
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Parental Underestimates of Child Weight: A Meta-analysis

TL;DR: Half of parents underestimated their children’s overweight/obese status and a significant minority underestimated children”s normal weight, indicating Pediatricians are well positioned to make efforts to remedy parental underestimates and promote adoption of healthy habits.
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What is metabolic syndrome, and why are children getting it?

TL;DR: Multiple environmental factors, in particular a typical Western diet, drive mitochondrial overload, while other changes in Western society, such as stress and sleep deprivation, increase insulin resistance and the propensity for food intake and drive the various elements of metabolic syndrome.
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Hydroxycinnamic acid derivatives: a potential class of natural compounds for the management of lipid metabolism and obesity.

TL;DR: In adipose tissues, hydroxycinnamic acid derivatives inhibit macrophage infiltration and nuclear factor κB (NF-κB) activation in obese animals and prevent adipocyte differentiation and lower lipid profile in experimental animals.
References
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Journal ArticleDOI

Establishing a standard definition for child overweight and obesity worldwide: international survey

TL;DR: The proposed cut off points, which are less arbitrary and more internationally based than current alternatives, should help to provide internationally comparable prevalence rates of overweight and obesity in children.
Journal Article

CDC growth charts; United States

TL;DR: Created with improved data and statistical curve smoothing procedures, the United States growth charts represent an enhanced instrument to evaluate the size and growth of infants and children.
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Childhood obesity: public-health crisis, common sense cure

TL;DR: In view of its rapid development in genetically stable populations, the childhood obesity epidemic can be primarily attributed to adverse environmental factors for which straightforward, if politically difficult, solutions exist.
Journal ArticleDOI

Prevalence of a metabolic syndrome phenotype in adolescents: findings from the third National Health and Nutrition Examination Survey, 1988-1994.

TL;DR: Perhaps 4% of adolescents and nearly 30% of overweight adolescents in the United States meet these criteria for a metabolic syndrome, a constellation of metabolic derangements associated with obesity, which may have significant implications for both public health and clinical interventions directed at this high-risk group of mostly overweight young people.
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