Journal ArticleDOI
Chitosan and its derivatives for gene delivery.
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TLDR
This review paper provides the recent development on chitosan derivatives available for gene delivery and its applications including the interaction and intracellular delivery of genetic materials.About:
This article is published in International Journal of Biological Macromolecules.The article was published on 2011-03-01. It has received 240 citations till now. The article focuses on the topics: Gene delivery.read more
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Recent advances on the development of wound dressings for diabetic foot ulcer treatment--a review.
TL;DR: This work reviews the state of the art and the most recent advances in the development of wound dressings for DFU treatment, with special emphasis given to systems employing new polymeric biomaterials, and to the latest and innovative therapeutic strategies and delivery approaches.
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Recent advances in nonviral vectors for gene delivery
Xia Guo,Leaf Huang +1 more
TL;DR: Novel nonviral vectors based on nucleic acids, typically based on cationic lipids or polymers, are classified as multifunctional hybrid nucleic acid vectors, novel membrane/core nanoparticles for nucleicacid delivery, and ultrasound-responsive nucleic Acid vectors.
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Chitosan as biomaterial in drug delivery and tissue engineering.
Saad M. Ahsan,Mathai Thomas,Kranthi K. Reddy,Sujata Gopal Sooraparaju,Amit Asthana,Ira Bhatnagar +5 more
TL;DR: The present article has tried to review the latest research on chitosan based tissue engineering constructs, drug delivery vehicles as well as dental care products to pave a way for future applications in the field of biomedical innovation and regenerative medicine.
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A review of chitosan and its derivatives in bone tissue engineering.
R. LogithKumar,A. KeshavNarayan,S. Dhivya,Anjali Chawla,Sekaran Saravanan,Nagarajan Selvamurugan +5 more
TL;DR: Current trends of using chitosan as a composite with other polymers and ceramics, and its modifications such as quaternization, carboxyalkylation, hydroxylated, phosphorylation, sulfation and copolymerization in bone tissue engineering are elaborated.
References
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Journal ArticleDOI
Oral gene delivery with chitosan--DNA nanoparticles generates immunologic protection in a murine model of peanut allergy.
TL;DR: It is demonstrated that oral allergen-gene immunization with chitosan–DNA nanoparticles is effective in modulating murine anaphylactic responses, and its prophylactic utility in treating food allergy is indicated.
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Novel chitin and chitosan nanofibers in biomedical applications.
TL;DR: This article reviews the recent reports on the preparation, properties and biomedical applications of chitin and chitosan based nanofibers in detail.
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Modulation of surface charge, particle size and morphological properties of chitosan-TPP nanoparticles intended for gene delivery.
TL;DR: This study demonstrates that systematic design and modulation of the surface charge and particle size of chitosan-TPP nanoparticles can be readily achieved with the right control of critical processing parameters, especially the chitOSan to TPP weight ratio.
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Chemical characteristics of O-carboxymethyl chitosans related to the preparation conditions
Xiguang Chen,Hyun Jin Park +1 more
TL;DR: In this article, the water insolubility of carboxymethyl chitosans at various pHs varied with the degree of the carboxyethylation and the reaction temperature, and the ratio of water/isopropanol in the reaction solvent.
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Sulfated chitin and chitosan as novel biomaterials
TL;DR: Sulfated chitin and chitosan are promising materials for biomedical applications according to current research and existing products and some new and futuristic approaches in this context area are discussed in detail.