Journal ArticleDOI
Cobalt-Catalyzed Sustainable Synthesis of Benzimidazoles by Redox-Economical Coupling of o-Nitroanilines and Alcohols.
TLDR
This study reveals cobalt catalyzed sustainable synthesis of benzimidazoles by redox-economical coupling of o-nitroanilines and alcohols by hydrogen autotransfer without using any additional external redox reagent and costly ligand system.Abstract:
This study reveals cobalt-catalyzed sustainable synthesis of benzimidazoles by redox-economical coupling of o-nitroanilines and alcohols. The major advantage of this report is the use of a commerci...read more
Citations
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Journal ArticleDOI
Recent Advancement on Sustainable Synthesis of N-heterocycles Following Acceptorless Dehydrogenative Coupling Protocol Using Alcohols
TL;DR: In this article, a review of homogeneous and heterogeneously catalyzed recent advancements in the synthesis of heterocycles following the transition metal-catalyzed acceptorless dehydrogenative coupling (ADC) approach is presented.
Journal ArticleDOI
Synthesis of N-Heterocycles via Oxidant-Free Dehydrocyclization of Alcohols Using Heterogeneous Catalysts.
TL;DR: In this paper, the authors summarize recent developments using both noble and non-noble metal-based heterogeneous catalysts to synthesize N-heterocycles from alcohols and N-nucleophiles via acceptorless dehydrogenation or borrowing hydrogen methodologies.
Journal ArticleDOI
Tandem transformations and multicomponent reactions utilizing alcohols following dehydrogenation strategy
TL;DR: In this review, the progress of tandem transformation of nitro, nitrile and azide functionalities as well as multi-component reactions utilizing alcohols is summarised and leads to the atom-economical synthesis of a wide range of alkylated imines, amines,Amides and N-heterocycles.
Journal ArticleDOI
Nickel-Catalyzed Direct Synthesis of Quinoxalines from 2-Nitroanilines and Vicinal Diols: Identifying Nature of the Active Catalyst
TL;DR: Inexpensive and simple NiBr2/1,10-phenanthroline system catalyzed synthesis of a series of quinoxalines from both 2-nitroanilines and 1,2-diamines is demonstrated.
References
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Journal ArticleDOI
Dehydrogenation as a substrate-activating strategy in homogeneous transition-metal catalysis.
Journal ArticleDOI
Applications of acceptorless dehydrogenation and related transformations in chemical synthesis.
TL;DR: Acceptorless dehydrogenation and related dehydrogenative coupling reactions have the potential for redirecting synthetic strategies to the use of sustainable resources, devoid of toxic reagents and deleterious side reactions, with no waste generation.
Journal ArticleDOI
The therapeutic journey of benzimidazoles: a review.
Yogita Bansal,Om Silakari +1 more
TL;DR: In the present review, various derivatives of benzimidazole with different pharmacological activities are described on the basis of substitution pattern around the nucleus with an aim to help medicinal chemists for developing an SAR on benzimdazole derived compounds for each activity.
Journal ArticleDOI
Substitution of alcohols by N-nucleophiles via transition metal-catalyzed dehydrogenation
Qin Yang,Qingfu Wang,Zhengkun Yu +2 more
TL;DR: This critical review summarizes the recent advances in "BH" substitution of alcohols by N-nucleophiles since 2009 and provides new principles for establishing green processes to replace the relevant traditional synthetic methods for C-N bond formation.
Journal ArticleDOI
First-Row Transition Metal (De)Hydrogenation Catalysis Based On Functional Pincer Ligands.
TL;DR: This review aims at providing a comprehensive picture of the utilization of functional pincer ligands in first-row transition metal hydrogenation and dehydrogenation catalysis and related synthetic concepts relying on these such as the hydrogen borrowing methodology.
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