Commentary: Representativeness is usually not necessary and often should be avoided
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This paper aims to demonstrate the efforts towards in-situ applicability of EMMARM, which aims to provide real-time information about individual patients’ cancer progression and Kessler’s disease progression.Abstract:
Cancer Epidemiology Unit, Department of Medical Sciences, University of Turin, Turin, Italy, Centre for Statistical Methodology, London School of Hygiene and Tropical Medicine, London, UK, Departments of Medical Statistics and Non-communicable Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK and Centre for Public Health Research, Massey University, Wellington, New Zealandread more
Citations
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Journal ArticleDOI
Comparison of Sociodemographic and Health-Related Characteristics of UK Biobank Participants With Those of the General Population.
Anna Fry,Thomas J. Littlejohns,Catherine Sudlow,Nicola Doherty,Ligia Adamska,Tim Sprosen,Rory Collins,Naomi E. Allen +7 more
TL;DR: UK Biobank is not representative of the sampling population; there is evidence of a “healthy volunteer” selection bias; valid assessment of exposure-disease relationships may be widely generalizable and does not require participants to be Representative of the population at large.
Journal ArticleDOI
Collider scope: when selection bias can substantially influence observed associations
TL;DR: In simulations, it is shown that even modest influences on selection into, or attrition from, a study can generate biased and potentially misleading estimates of both phenotypic and genotypic associations.
Journal ArticleDOI
Comparison of risk factor associations in UK Biobank against representative, general population based studies with conventional response rates: prospective cohort study and individual participant meta-analysis
G. David Batty,G. David Batty,Catharine R. Gale,Catharine R. Gale,Mika Kivimäki,Ian J. Deary,Steven Bell,Steven Bell,Steven Bell +8 more
TL;DR: Risk factor levels and mortality rates were typically more favourable in UK Biobank participants relative to the HSE-SHS consortium, and close agreement was seen between studies.
Journal ArticleDOI
An integrated national mortality surveillance system for death registration and mortality surveillance, China.
Shiwei Liu,Xiaoling Wu,Alan D. Lopez,Lijun Wang,Yue Cai,Andrew Page,Peng Yin,Yunning Liu,Yichong Li,Jiangmei Liu,Jinling You,Maigeng Zhou +11 more
TL;DR: The development and operation of the new national mortality surveillance system is described, which is expected to yield representative provincial estimates of mortality in China for the first time.
Journal ArticleDOI
Perils and potentials of self‐selected entry to epidemiological studies and surveys
Niels Keiding,Thomas A. Louis +1 more
TL;DR: It is a good time for statisticians to take stock of their role and position regarding surveys, observational research in epidemiology and clinical studies, and whether conditional effects in the sample may be transported to desired target populations.
References
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M. I. Asher,U. Keil,H. R. Anderson,Richard Beasley,J. Crane,Fernando D. Martinez,Ed A. Mitchell,Neil Pearce,B. Sibbald,Alistair Stewart,David P. Strachan,Stephan K. Weiland,Hywel C Williams +12 more
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Why representativeness should be avoided
TL;DR: The essence of knowledge is generalisation; that rubbing wood in a certain way can produce fire is a knowledge derived by generalisation from individual experiences.
Journal ArticleDOI
Mortality in Relation to Smoking: Ten Years' Observations of British Doctors
Richard Doll,A B Hill +1 more
TL;DR: Evidence supports the claim that cigarette smoking is one of the causes of coronary thrombosis under age 75 and continued smoking may prevent or delay the healing of a chronic gastric ulcer and thereby it may increase the mortality rate.