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Comparative study of antibiofilm activity of copper oxide and iron oxide nanoparticles against multidrug resistant biofilm forming uropathogens.

TLDR
The metal oxide nanoparticles viz.
Abstract
The effectiveness of the metal oxide nanoparticles viz. CuO and Fe2O3 as antibacterial agents against multidrug resistant biofilm forming bacteria was evaluated. CuO nanoparticles were also experimented for antibiofilm and time kill assay. The CuO displayed maximum antibacterial activity with zone of inhibition of (22 ± 1) mm against methicillin resistant Staphylococcus aureus (MRSA) followed by Escherichia coli (18 ± 1) mm. The Fe2O3 showed the zone of inhibition against MRSA of (14 ± 1) mm followed by E. coli (12 ± 1) mm. CuO proved to be more toxic than Fe2O3 nanoparticles showing significantly high antibacterial activity and found to possess dose dependent antibiofilm properties.

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Journal ArticleDOI

Alternative Antimicrobial Approach: Nano-Antimicrobial Materials

TL;DR: The activities of nanoparticles as an antimicrobial means, their mode of action, nanoparticle effect on drug-resistant bacteria, and the risks attendant on their use as antibacterial agents are discussed.
Journal ArticleDOI

Metal oxide nanoparticles as antimicrobial agents: a promise for the future

TL;DR: The mechanisms of action of MeO-NPs against micro-organisms, safety concerns, challenges and future perspectives are discussed.
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Quorum sensing inhibitors as antipathogens: biotechnological applications.

TL;DR: The use of QSIs to counter diseases in humans as well as plants and animals of economic importance is focused on and the challenges encountered are discussed.
Journal ArticleDOI

Metal Oxide Nanoparticles as Biomedical Materials

TL;DR: In this review, a comprehensive review of researches on metal oxide nanoparticles, their nanoscale physicochemical properties, defining specific applications in the various fields of nanomedicine are provided.
Journal ArticleDOI

Metal Oxide Nanoparticles Against Bacterial Biofilms: Perspectives and Limitations.

TL;DR: A comparative analysis of antibiofilm properties of various metal oxide NPs and nanocomposites and mechanisms of their effect on plankton bacteria cells and biofilms are presented.
References
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Reference EntryDOI

Growing and analyzing static biofilms

TL;DR: In this article, the early stages of biofilm formation are examined using static biofilm assays, which are suitable for either small or relatively large-scale studies and can be used individually or in combination for the study of biofilms.
Journal ArticleDOI

Quorum sensing inhibitors: an overview.

TL;DR: This review focuses primarily on natural and synthetic quorum sensing inhibitors (QSIs) with the potential for treating bacterial infections and it has been opined that the most versatile prokaryotes to produce QSI are likely to be those, which are generally regarded as safe.
Journal ArticleDOI

Quenching the quorum sensing system: potential antibacterial drug targets

TL;DR: The biodiversity of organisms with potential to quench QS signals and the use of QQ molecules as antibacterial drugs have been reviewed.
Journal ArticleDOI

Evolution of Resistance to Quorum-Sensing Inhibitors

TL;DR: Efforts to target signal molecules and their receptors have proved effective in alleviating the virulent behavior of such pathogenic bacteria, but evidence is accumulating that bacteria may develop resistance to QSIs.
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