Journal ArticleDOI
Compartmental analysis of compliance and outflow resistance of the cerebrospinal fluid system
TLDR
The distribution of compliance and outflow resistance between cerebral and spinal compartments was measured in anesthetized, ventilated cats by analysis of the cerebrospinal fluid (CSF) pressure response to changes in CSF volume.Abstract:
✓ The distribution of compliance and outflow resistance between cerebral and spinal compartments was measured in anesthetized, ventilated cats by analysis of the cerebrospinal fluid (CSF) pressure response to changes in CSF volume. Cerebral and spinal compartments were isolated by inflating a balloon positioned epidurally at the level of C-6. The change of CSF volume per unit change in pressure (compliance) and change of CSF volume per unit of time (absorption) were evaluated by inserting pressure data from the experimental responses into a series of equations developed from a mathematical model. It was found that 68% of total compliance is contributed by the cerebral compartment while the remaining 32% is contained within the spinal axis. The cerebral compartment accounted for 84% of total CSF absorption. The mechanism for spinal absorption appears to be similar in that no differences were obvious on the basis of pressure dynamics.read more
Citations
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Assessment of cerebrospinal fluid system dynamics : novel infusion protocol, mathematical modelling and parameter estimation for hydrocephalus investigations
TL;DR: Patients with idiopathic normal pressure hydrocephalus (INPH) have a disturbance in the cerebrospinal fluid (CSF) system – a shunt is placed in the CSF system.
DissertationDOI
Adaptive shunts for cerebrospinal fluid control
TL;DR: The brain is surrounded by the water-like and colorless cerebrospinal fluid (CSF), which protects the brain from impacts, supports it by buoyancy forces, provides nutrients and removes waste products, and a mismatch of CSF production and resorption leads to hydrocephalus.
Dissertation
Modellierung, Analyse und Berechnung der zerebrovaskularen Regulationsmechanismen
TL;DR: In this paper, a mathematical model for the zerebralen Hamodynamik des Menschen is presented, e.g., a ratte stabiler is used in order to cope with Schadel-Hirn-Trauma.
Journal ArticleDOI
[The alteration of perfusion pressure and cerebral circulation during intracranial hypertension caused by inflation of balloons in the infar- and supratentorial spaces (author's transl)].
TL;DR: In 40 mongrel dogs under pentobarbital anesthesia with artificial respiration, pressures were continuously recorded during intracranial hypertension induced by incremental inflation of the extradural balloon placed at the right frontal region or at the posterior fossa to study the mechanism of alteration of cerebral circulation.
Book ChapterDOI
Validity of Measurements of CSF Outflow Resistance Estimated by the Bolus Injection Method
J. D. Miller,H. Takizawa +1 more
TL;DR: This series of experiments was planned to compare the steadystate infusion and bolus injection methods under normal conditions and during saline loading of the CSF space, carried out so as to increase the elastance of theCSF system artificially.
References
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Journal ArticleDOI
A simple constant‐infusion manometric test for measurement of CSF absorption: I. Rationale and method
Robert Katzman,Francis Hussey +1 more
Journal ArticleDOI
The pressure-volume curve of the cerebrospinal fluid space in dogs
TL;DR: The cerebrospinal fluid pressure‐volume curve was determined by measuring the pressure response to rapid injection of fluid into the cisterna magna of dogs, by means of a constant flow infusion pump.
Journal ArticleDOI
Cranial and spinal components of the cerebrospinal fluid pressure‐volume curve
Jan Löfgren,Nicolaus N. Zwetnow +1 more
TL;DR: A quantitative analysis of the contributions of the cranial and spinal compartments to the cerebrospinal fluid pressure‐volume curve was made using dogs using dogs to represent the effects on the fluid pressure of forced alterations in the volume of the intracranial vascular bed.
Journal ArticleDOI
The mechanism of the change in cerebrospinal fluid pressure following an induced change in the volume of the fluid space.
Henry W. Ryder,Frank F. Espey,Fariss D. Kimbell,Ernest J. Penka,Adolf Rosenauer,Boris Podolsky,Joseph P. Evans +6 more
Journal ArticleDOI
Pressure-Volume Considerations in Infantile Hydrocephalus
Kenneth Shulman,Anthony Marmarou +1 more
TL;DR: Evidence of normal ventricular pressure does not exclude the possibility of progressive hydrocephalus, and increased pressure is likely to occur for quite long periods while the hydrocephalic infant is engaged in normal infantile activities.
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A simple constant‐infusion manometric test for measurement of CSF absorption: I. Rationale and method
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