Journal ArticleDOI
Compartmental analysis of compliance and outflow resistance of the cerebrospinal fluid system
TLDR
The distribution of compliance and outflow resistance between cerebral and spinal compartments was measured in anesthetized, ventilated cats by analysis of the cerebrospinal fluid (CSF) pressure response to changes in CSF volume.Abstract:
✓ The distribution of compliance and outflow resistance between cerebral and spinal compartments was measured in anesthetized, ventilated cats by analysis of the cerebrospinal fluid (CSF) pressure response to changes in CSF volume. Cerebral and spinal compartments were isolated by inflating a balloon positioned epidurally at the level of C-6. The change of CSF volume per unit change in pressure (compliance) and change of CSF volume per unit of time (absorption) were evaluated by inserting pressure data from the experimental responses into a series of equations developed from a mathematical model. It was found that 68% of total compliance is contributed by the cerebral compartment while the remaining 32% is contained within the spinal axis. The cerebral compartment accounted for 84% of total CSF absorption. The mechanism for spinal absorption appears to be similar in that no differences were obvious on the basis of pressure dynamics.read more
Citations
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Book ChapterDOI
The Patient with an Intracranial Tumor
TL;DR: A 49-year-old right-handed man came to the hospital complaining of right-sided weakness and dysphagia and gave a long history of hypertension.
Journal ArticleDOI
Anaesthesia for craniotomy
TL;DR: A better appreciation of post-operative pain and the effects of conventional analgesics, morphine and paracetamol will improve patient care and Morphine, which was previously considered to be contraindicated, is safe to use when given appropriately.
Proceedings ArticleDOI
Simulation of CSF pressure/volume characteristics
I.R. Greenshields,F. di Mario +1 more
TL;DR: Current research into the development of a compartmentalized cerebrospinal fluid (CSF) pressure/volume model with applications in modeling the pathogenesis of communicating hydrocephalus is described.
Dissertation
Modeling the Interaction between Intracranial Pressure and Cerebral Hemodynamics
TL;DR: A simple mathematical model is chosen and the results indicate that although the model contains several parameters, only four of them seem to influence ICP most and the effect of each parameter on ICP and correlation among these parameters provide valuable information about patient's status.
Journal ArticleDOI
Quantification of the Disturbed Cerebrospinal Fluid Circulation and the Elasticity after Subarachnoid Hemorrhage, using Infusion Studies
TL;DR: The results of a preliminary trial to apply infusion studies as a method of quantifying the amount of CSF circulatory disturbance and the elasticity of the brain were reported in this paper.
References
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Journal ArticleDOI
A simple constant‐infusion manometric test for measurement of CSF absorption: I. Rationale and method
Robert Katzman,Francis Hussey +1 more
Journal ArticleDOI
The pressure-volume curve of the cerebrospinal fluid space in dogs
TL;DR: The cerebrospinal fluid pressure‐volume curve was determined by measuring the pressure response to rapid injection of fluid into the cisterna magna of dogs, by means of a constant flow infusion pump.
Journal ArticleDOI
Cranial and spinal components of the cerebrospinal fluid pressure‐volume curve
Jan Löfgren,Nicolaus N. Zwetnow +1 more
TL;DR: A quantitative analysis of the contributions of the cranial and spinal compartments to the cerebrospinal fluid pressure‐volume curve was made using dogs using dogs to represent the effects on the fluid pressure of forced alterations in the volume of the intracranial vascular bed.
Journal ArticleDOI
The mechanism of the change in cerebrospinal fluid pressure following an induced change in the volume of the fluid space.
Henry W. Ryder,Frank F. Espey,Fariss D. Kimbell,Ernest J. Penka,Adolf Rosenauer,Boris Podolsky,Joseph P. Evans +6 more
Journal ArticleDOI
Pressure-Volume Considerations in Infantile Hydrocephalus
Kenneth Shulman,Anthony Marmarou +1 more
TL;DR: Evidence of normal ventricular pressure does not exclude the possibility of progressive hydrocephalus, and increased pressure is likely to occur for quite long periods while the hydrocephalic infant is engaged in normal infantile activities.
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