Journal ArticleDOI
Compartmental analysis of compliance and outflow resistance of the cerebrospinal fluid system
TLDR
The distribution of compliance and outflow resistance between cerebral and spinal compartments was measured in anesthetized, ventilated cats by analysis of the cerebrospinal fluid (CSF) pressure response to changes in CSF volume.Abstract:
✓ The distribution of compliance and outflow resistance between cerebral and spinal compartments was measured in anesthetized, ventilated cats by analysis of the cerebrospinal fluid (CSF) pressure response to changes in CSF volume. Cerebral and spinal compartments were isolated by inflating a balloon positioned epidurally at the level of C-6. The change of CSF volume per unit change in pressure (compliance) and change of CSF volume per unit of time (absorption) were evaluated by inserting pressure data from the experimental responses into a series of equations developed from a mathematical model. It was found that 68% of total compliance is contributed by the cerebral compartment while the remaining 32% is contained within the spinal axis. The cerebral compartment accounted for 84% of total CSF absorption. The mechanism for spinal absorption appears to be similar in that no differences were obvious on the basis of pressure dynamics.read more
Citations
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Journal ArticleDOI
Brain compliance: the old story with a new ‘et cetera’
Marek Czosnyka,Giuseppe Citerio +1 more
Journal ArticleDOI
Hypothesis about the physiopathology of acute deterioration and sudden death caused by colloid cysts of the third ventricle.
TL;DR: It seems possible that acute deterioration is initiated by an increase in sagittal sinus pressure, which provokes acute brain swelling, with a series of often-irreversible events, leading to sudden death.
Journal ArticleDOI
Pressure-volume conditions in patients with subarachnoid and/or intraventricular hemorrhage
TL;DR: An equation was derived from the PVI model that describes the relationship between the Psyst:Pdiast ratio and the P VI that increases ICP from the diastolic to the systolic level and does not correlate with ICP.
Journal ArticleDOI
Quasi-steady-state compartmental model of intracranial fluid dynamics.
TL;DR: A lumped-parameter compartmental model for the cerebrovascular fluid system is constructed and solved for quasi-steady-state flow and predicts the pressure waves in the various compartments of the intracranial region in response to changes in the arterial pressure.
Journal ArticleDOI
Impaired pulsation absorber mechanism in idiopathic normal pressure hydrocephalus: laboratory investigation.
TL;DR: The results suggest that the human intracranial system shows frequency dependence as seen in animal experiments and imply that reduced frequency-dependent compliance may be responsible for elevated ICP amplitude observed in patients who respond to CSF shunting.
References
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Journal ArticleDOI
A simple constant‐infusion manometric test for measurement of CSF absorption: I. Rationale and method
Robert Katzman,Francis Hussey +1 more
Journal ArticleDOI
The pressure-volume curve of the cerebrospinal fluid space in dogs
TL;DR: The cerebrospinal fluid pressure‐volume curve was determined by measuring the pressure response to rapid injection of fluid into the cisterna magna of dogs, by means of a constant flow infusion pump.
Journal ArticleDOI
Cranial and spinal components of the cerebrospinal fluid pressure‐volume curve
Jan Löfgren,Nicolaus N. Zwetnow +1 more
TL;DR: A quantitative analysis of the contributions of the cranial and spinal compartments to the cerebrospinal fluid pressure‐volume curve was made using dogs using dogs to represent the effects on the fluid pressure of forced alterations in the volume of the intracranial vascular bed.
Journal ArticleDOI
The mechanism of the change in cerebrospinal fluid pressure following an induced change in the volume of the fluid space.
Henry W. Ryder,Frank F. Espey,Fariss D. Kimbell,Ernest J. Penka,Adolf Rosenauer,Boris Podolsky,Joseph P. Evans +6 more
Journal ArticleDOI
Pressure-Volume Considerations in Infantile Hydrocephalus
Kenneth Shulman,Anthony Marmarou +1 more
TL;DR: Evidence of normal ventricular pressure does not exclude the possibility of progressive hydrocephalus, and increased pressure is likely to occur for quite long periods while the hydrocephalic infant is engaged in normal infantile activities.
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