Journal ArticleDOI
Compartmental analysis of compliance and outflow resistance of the cerebrospinal fluid system
TLDR
The distribution of compliance and outflow resistance between cerebral and spinal compartments was measured in anesthetized, ventilated cats by analysis of the cerebrospinal fluid (CSF) pressure response to changes in CSF volume.Abstract:
✓ The distribution of compliance and outflow resistance between cerebral and spinal compartments was measured in anesthetized, ventilated cats by analysis of the cerebrospinal fluid (CSF) pressure response to changes in CSF volume. Cerebral and spinal compartments were isolated by inflating a balloon positioned epidurally at the level of C-6. The change of CSF volume per unit change in pressure (compliance) and change of CSF volume per unit of time (absorption) were evaluated by inserting pressure data from the experimental responses into a series of equations developed from a mathematical model. It was found that 68% of total compliance is contributed by the cerebral compartment while the remaining 32% is contained within the spinal axis. The cerebral compartment accounted for 84% of total CSF absorption. The mechanism for spinal absorption appears to be similar in that no differences were obvious on the basis of pressure dynamics.read more
Citations
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Book ChapterDOI
ICP Monitoring and Phase-Contrast MRI to Investigate Intracranial Compliance.
Armelle Lokossou,Olivier Balédent,Simon Garnotel,Gwenaël Pagé,Laurent Balardy,Zofia Czosnyka,Pierre Payoux,Eric A. Schmidt +7 more
TL;DR: During "basal" condition, the compliance amplitude of the intracranial compartment is heterogeneous in suspected hydrocephalus patients, and its value is lower than expected; this new parameter could represent new information, complementary to conventional infusion tests.
Book ChapterDOI
Hydrocephalus — Analysis of 480 Infusion Tests
G. Costabile,Ch. Probst +1 more
TL;DR: Since long term ventricular cerebrospinal fluid (CSF) drainage only increases the CSF outflow, it comes to aid of patients with communicating ventricular enlargement only if the pathological changes depend on a decrease of CSFOutflow.
Journal ArticleDOI
The contribution of arachidonic acid to the aetiology and pathophysiology of focal brain oedema; studies using an infusion oedema model.
TL;DR: It is suggested that free intraparenchymal arachidonic acid, at concentrations exceeding those occurring in most neuropathological conditions, can increase the normal brain paren chymal capillary permeability but does not disrupt focal cerebrovascular and electrophysiological function.
Dissertation
Finite element simulation of a poroelastic model of the CSF system in the human brain during an infusion test
TL;DR: A two-fluid poroelastic model of the brain in which CSF pressure pulsations are linked to arterial blood pressure pulsation is developed further and simulation results are compared to clinical data.
Book ChapterDOI
Anterior Fontanelle Pressure Monitoring in Infants
W. C. G. Overweg-Plandsoen,D. A. de Jong,M. C. B. Loonen,C. J. J. Avezaat,J. H. M. van Eindhoven,P. G. H. Mulder +5 more
TL;DR: In children with an open fontanelle there is a natural access to the intracranial compartment; therefore, non-invasive anteriorfontanelle pressure (AFP) monitoring seems an ideal method for measuring ICP.
References
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Journal ArticleDOI
A simple constant‐infusion manometric test for measurement of CSF absorption: I. Rationale and method
Robert Katzman,Francis Hussey +1 more
Journal ArticleDOI
The pressure-volume curve of the cerebrospinal fluid space in dogs
TL;DR: The cerebrospinal fluid pressure‐volume curve was determined by measuring the pressure response to rapid injection of fluid into the cisterna magna of dogs, by means of a constant flow infusion pump.
Journal ArticleDOI
Cranial and spinal components of the cerebrospinal fluid pressure‐volume curve
Jan Löfgren,Nicolaus N. Zwetnow +1 more
TL;DR: A quantitative analysis of the contributions of the cranial and spinal compartments to the cerebrospinal fluid pressure‐volume curve was made using dogs using dogs to represent the effects on the fluid pressure of forced alterations in the volume of the intracranial vascular bed.
Journal ArticleDOI
The mechanism of the change in cerebrospinal fluid pressure following an induced change in the volume of the fluid space.
Henry W. Ryder,Frank F. Espey,Fariss D. Kimbell,Ernest J. Penka,Adolf Rosenauer,Boris Podolsky,Joseph P. Evans +6 more
Journal ArticleDOI
Pressure-Volume Considerations in Infantile Hydrocephalus
Kenneth Shulman,Anthony Marmarou +1 more
TL;DR: Evidence of normal ventricular pressure does not exclude the possibility of progressive hydrocephalus, and increased pressure is likely to occur for quite long periods while the hydrocephalic infant is engaged in normal infantile activities.
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A simple constant‐infusion manometric test for measurement of CSF absorption: I. Rationale and method
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