Journal ArticleDOI
Compartmental analysis of compliance and outflow resistance of the cerebrospinal fluid system
TLDR
The distribution of compliance and outflow resistance between cerebral and spinal compartments was measured in anesthetized, ventilated cats by analysis of the cerebrospinal fluid (CSF) pressure response to changes in CSF volume.Abstract:
✓ The distribution of compliance and outflow resistance between cerebral and spinal compartments was measured in anesthetized, ventilated cats by analysis of the cerebrospinal fluid (CSF) pressure response to changes in CSF volume. Cerebral and spinal compartments were isolated by inflating a balloon positioned epidurally at the level of C-6. The change of CSF volume per unit change in pressure (compliance) and change of CSF volume per unit of time (absorption) were evaluated by inserting pressure data from the experimental responses into a series of equations developed from a mathematical model. It was found that 68% of total compliance is contributed by the cerebral compartment while the remaining 32% is contained within the spinal axis. The cerebral compartment accounted for 84% of total CSF absorption. The mechanism for spinal absorption appears to be similar in that no differences were obvious on the basis of pressure dynamics.read more
Citations
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Journal ArticleDOI
Intracranial pressure monitoring.
TL;DR: The problems with the technique are that the brain must be punctured, opening the possibilities, and the technique remains the standard against which all other methods must be judged.
Journal ArticleDOI
Granulocytes in the subarachnoid space of humans and rabbits with bacterial meningitis undergo apoptosis and are eliminated by macrophages
Roland Nau,U. Zettl,Joachim Gerber,Frank Trostdorf,Uwe Michel,Tobias Böttcher,Holger Schmidt,Silke Adler,Wolfgang Brück +8 more
TL;DR: During resolution of subarachnoid space inflammation in bacterial meningitis, a substantial fraction of granulocyte undergoes apoptosis, and these granulocytes are removed by phagocytosis by macrophages.
Book ChapterDOI
A Method for Predicting PVI in Normal Patients
TL;DR: The present study was undertaken to define normal values in humans using pressure-Volume Index and bolus techniques for measuring neural axis pressure-volume relationships and characterizing CSF hydrodynamics.
Journal ArticleDOI
Pathophysiological correlates in bacterial meningitis
TL;DR: This review summarises briefly several areas of importance in the pathogenesis of bacterial meningitis.
Journal ArticleDOI
The effect of cerebrospinal fluid drainage on cerebral perfusion in traumatic brain injured adults.
Mary E. Kerr,Donald W. Marion,Susan M. Sereika,Barbara B. Weber,Patricia A. Orndoff,Richard Henker,Jack E. Wilberger +6 more
TL;DR: Cerebrospinal fluid drainage provides a transient decrease in intracranial pressure without a measurable improvement in other indices of cerebral perfusion, as well as identifying factors that impact treatment effectiveness.
References
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Journal ArticleDOI
A simple constant‐infusion manometric test for measurement of CSF absorption: I. Rationale and method
Robert Katzman,Francis Hussey +1 more
Journal ArticleDOI
The pressure-volume curve of the cerebrospinal fluid space in dogs
TL;DR: The cerebrospinal fluid pressure‐volume curve was determined by measuring the pressure response to rapid injection of fluid into the cisterna magna of dogs, by means of a constant flow infusion pump.
Journal ArticleDOI
Cranial and spinal components of the cerebrospinal fluid pressure‐volume curve
Jan Löfgren,Nicolaus N. Zwetnow +1 more
TL;DR: A quantitative analysis of the contributions of the cranial and spinal compartments to the cerebrospinal fluid pressure‐volume curve was made using dogs using dogs to represent the effects on the fluid pressure of forced alterations in the volume of the intracranial vascular bed.
Journal ArticleDOI
The mechanism of the change in cerebrospinal fluid pressure following an induced change in the volume of the fluid space.
Henry W. Ryder,Frank F. Espey,Fariss D. Kimbell,Ernest J. Penka,Adolf Rosenauer,Boris Podolsky,Joseph P. Evans +6 more
Journal ArticleDOI
Pressure-Volume Considerations in Infantile Hydrocephalus
Kenneth Shulman,Anthony Marmarou +1 more
TL;DR: Evidence of normal ventricular pressure does not exclude the possibility of progressive hydrocephalus, and increased pressure is likely to occur for quite long periods while the hydrocephalic infant is engaged in normal infantile activities.
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