Journal ArticleDOI
Compartmental analysis of compliance and outflow resistance of the cerebrospinal fluid system
TLDR
The distribution of compliance and outflow resistance between cerebral and spinal compartments was measured in anesthetized, ventilated cats by analysis of the cerebrospinal fluid (CSF) pressure response to changes in CSF volume.Abstract:
✓ The distribution of compliance and outflow resistance between cerebral and spinal compartments was measured in anesthetized, ventilated cats by analysis of the cerebrospinal fluid (CSF) pressure response to changes in CSF volume. Cerebral and spinal compartments were isolated by inflating a balloon positioned epidurally at the level of C-6. The change of CSF volume per unit change in pressure (compliance) and change of CSF volume per unit of time (absorption) were evaluated by inserting pressure data from the experimental responses into a series of equations developed from a mathematical model. It was found that 68% of total compliance is contributed by the cerebral compartment while the remaining 32% is contained within the spinal axis. The cerebral compartment accounted for 84% of total CSF absorption. The mechanism for spinal absorption appears to be similar in that no differences were obvious on the basis of pressure dynamics.read more
Citations
More filters
Journal ArticleDOI
A model for studies of intracranial volume pressure dynamics in traumatic brain injury.
TL;DR: It is shown that it is possible to vary ICP dynamics in a traumatic brain injury model without causing pathological increases in baseline ICP, which may be used to study the effects of secondary insults on the injured brain when ICP is normal but intracranial compensatory volume is impaired.
Journal ArticleDOI
Spontaneous Intracranial Hypotension Without CSF Leakage-Concept of a Pathological Cranial to Spinal Fluid Shift.
Johannes Goldberg,Levin Häni,Christopher Marvin Jesse,Irena Zubak,Eike I. Piechowiak,Jan Gralla,Tomas Dobrocky,Jürgen Beck,Andreas Raabe +8 more
TL;DR: In this article, a pathophysiological concept for the subgroup of SIH patients with typical cranial imaging findings and no evidence of CSF leakage was proposed, where a combination of pathologically increased spinal compliance, decreased intracranial CSF volume, low CSF outflow resistance, and decreased venous pressure might result in a pathological orthostatic cranial-to-spinal CSF shift.
Journal ArticleDOI
Pressure-Volume Relationships in the Spinal Canal and Potential Neurological Complications After Epidural Fluid Injections
TL;DR: Data obtained from the scientific literature and direct clinical observation is used to derive a first-order approximation of epidural, subarachnoid, and intracranial pressure responses to epidural fluid injections.
Book ChapterDOI
Intraventricular Pressure Monitoring and CSF Dynamics in Non-Tumor Aqueductal Stenosis
TL;DR: This work analyzes intraventricular pressure (IVP) and CSF Pressure/Volume relationships in 17 juvenile and adult patients affected by non-tumor aqueductal stenosis and demonstrates the degree of hydrocephalus and the site of the aqueductive stricture.
References
More filters
Journal ArticleDOI
A simple constant‐infusion manometric test for measurement of CSF absorption: I. Rationale and method
Robert Katzman,Francis Hussey +1 more
Journal ArticleDOI
The pressure-volume curve of the cerebrospinal fluid space in dogs
TL;DR: The cerebrospinal fluid pressure‐volume curve was determined by measuring the pressure response to rapid injection of fluid into the cisterna magna of dogs, by means of a constant flow infusion pump.
Journal ArticleDOI
Cranial and spinal components of the cerebrospinal fluid pressure‐volume curve
Jan Löfgren,Nicolaus N. Zwetnow +1 more
TL;DR: A quantitative analysis of the contributions of the cranial and spinal compartments to the cerebrospinal fluid pressure‐volume curve was made using dogs using dogs to represent the effects on the fluid pressure of forced alterations in the volume of the intracranial vascular bed.
Journal ArticleDOI
The mechanism of the change in cerebrospinal fluid pressure following an induced change in the volume of the fluid space.
Henry W. Ryder,Frank F. Espey,Fariss D. Kimbell,Ernest J. Penka,Adolf Rosenauer,Boris Podolsky,Joseph P. Evans +6 more
Journal ArticleDOI
Pressure-Volume Considerations in Infantile Hydrocephalus
Kenneth Shulman,Anthony Marmarou +1 more
TL;DR: Evidence of normal ventricular pressure does not exclude the possibility of progressive hydrocephalus, and increased pressure is likely to occur for quite long periods while the hydrocephalic infant is engaged in normal infantile activities.
Related Papers (5)
A nonlinear analysis of the cerebrospinal fluid system and intracranial pressure dynamics.
Continuous recording and control of ventricular fluid pressure in neurosurgical practice.
A simple constant‐infusion manometric test for measurement of CSF absorption: I. Rationale and method
Robert Katzman,Francis Hussey +1 more