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Journal ArticleDOI

Compartmental analysis of compliance and outflow resistance of the cerebrospinal fluid system

Anthony Marmarou, +2 more
- 01 Nov 1975 - 
- Vol. 43, Iss: 5, pp 523-534
TLDR
The distribution of compliance and outflow resistance between cerebral and spinal compartments was measured in anesthetized, ventilated cats by analysis of the cerebrospinal fluid (CSF) pressure response to changes in CSF volume.
Abstract
✓ The distribution of compliance and outflow resistance between cerebral and spinal compartments was measured in anesthetized, ventilated cats by analysis of the cerebrospinal fluid (CSF) pressure response to changes in CSF volume. Cerebral and spinal compartments were isolated by inflating a balloon positioned epidurally at the level of C-6. The change of CSF volume per unit change in pressure (compliance) and change of CSF volume per unit of time (absorption) were evaluated by inserting pressure data from the experimental responses into a series of equations developed from a mathematical model. It was found that 68% of total compliance is contributed by the cerebral compartment while the remaining 32% is contained within the spinal axis. The cerebral compartment accounted for 84% of total CSF absorption. The mechanism for spinal absorption appears to be similar in that no differences were obvious on the basis of pressure dynamics.

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Citations
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CSF dynamics in a rodent model of closed head injury.

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Anatomical and biomechanical similarity in intracranial environment in identical twins with external hydrocephalus.

TL;DR: The results indicate that identical twins with external hydrocephalus have very similar intracranial environments, both anatomically and bio-mechanically.
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Cerebral Circulation and Brain

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Simulation of cerebrospinal fluid transport

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Idiopathischer Normaldruckhydrozephalus

TL;DR: In this article, weielsetzung des Liquorflusses im Aquaeductus cerebri zur Diagnostizierung des idiopathischen Normaldruckhydrozephalus (iNPH) is discussed.
References
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Journal ArticleDOI

The pressure-volume curve of the cerebrospinal fluid space in dogs

TL;DR: The cerebrospinal fluid pressure‐volume curve was determined by measuring the pressure response to rapid injection of fluid into the cisterna magna of dogs, by means of a constant flow infusion pump.
Journal ArticleDOI

Cranial and spinal components of the cerebrospinal fluid pressure‐volume curve

TL;DR: A quantitative analysis of the contributions of the cranial and spinal compartments to the cerebrospinal fluid pressure‐volume curve was made using dogs using dogs to represent the effects on the fluid pressure of forced alterations in the volume of the intracranial vascular bed.
Journal ArticleDOI

Pressure-Volume Considerations in Infantile Hydrocephalus

TL;DR: Evidence of normal ventricular pressure does not exclude the possibility of progressive hydrocephalus, and increased pressure is likely to occur for quite long periods while the hydrocephalic infant is engaged in normal infantile activities.
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