Journal ArticleDOI
Complementarity between Rous sarcoma virus (RSV) RNA and the in vitro-synthesized DNA of the virus-associated DNA polymerase.
Peter H. Duesberg,E. Canaani +1 more
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This article is published in Virology.The article was published on 1970-11-01. It has received 96 citations till now. The article focuses on the topics: Hepatitis B virus DNA polymerase & RNA-dependent RNA polymerase.read more
Citations
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Journal ArticleDOI
RNA-directed DNA synthesis by virions of Rous sarcoma virus: Further characterization of the templates and the extent of their transcription
TL;DR: Results further substantiate the occurrence of preferential transcription from a limited region of the viral genome as defined previously for double-stranded enzymatic product by measurement of reassociation kinetics and facilitates the study of nucleic acid homologies among RNA tumor virus genomes.
Journal ArticleDOI
Role of subunits of 60 to 70S avian tumor virus ribonucleic acid in its template activity for the viral deoxyribonucleic acid polymerase.
Eli Canaani,Peter H. Duesberg +1 more
TL;DR: It was concluded that neither the 30 to 40S subunits nor most of the 4S subunit fraction of 60 to 70S RSV RNA contribute much as primers to the template activity of the RNA.
Journal ArticleDOI
Avian acute leukemia viruses MC29 and MH2 share specific RNA sequences: Evidence for a second class of transforming genes
Peter H. Duesberg,Peter K. Vogt +1 more
TL;DR: It is concluded that the specific sequences of MH2 and MC29 are related, and it is proposed that they are necessary for, or identical with, the onc genes of these viruses.
Journal ArticleDOI
Detection of Avian Tumor Virus RNA in Uninfected Chicken Embryo Cells
TL;DR: Uninfected chicken embryo cells were analyzed for the presence of viral RNA by molecular hybridization with the single-stranded deoxyribonucleic acid (DNA) product of the RNA-dependent DNA polymerase contained in avian sarcoma-leukosis virions, and the viral RNA content correlated with the level of helper activity in the cells.
Book ChapterDOI
RNA-directed DNA polymerase--properties and functions in oncogenic RNA viruses and cells.
Maurice Green,Gary F. Gerard +1 more
TL;DR: The chapter provides evidence for the in vivo function of the viral RNA→DNA polymerase and a concise description of the present understanding of the molecular events of oncornavirus replication and cell transformation.
References
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Journal ArticleDOI
Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of RNA Tumour Viruses
TL;DR: Two independent groups of investigators have found evidence of an enzyme in virions of RNA tumour viruses which synthesizes DNA from an RNA template, apparently the classical process of information transfer from DNA to RNA can be inverted.
Journal ArticleDOI
RNA-dependent DNA polymerase in virions of Rous sarcoma virus.
Howard M. Temin,Satoshi Mizutani +1 more
TL;DR: Viral RNA-dependent DNA Polymerase: RNA- dependent DNA polymerase in Virions of Rous Sarcoma Virus and its role in cell reprograming is studied.
Journal ArticleDOI
Formation and properties of RNA-DNA complexes*
A.P. Nygaard,B.D. Hall +1 more
TL;DR: The rate of formation of complexes between T2 RNA and T2 DNA has been measured at various salt concentrations and temperatures and the resistance to RNase increased with increasing salt concentration but was not complete under any condition tested.
Journal ArticleDOI
Characterization of the products of DNA-directed DNA polymerases in oncogenic RNA viruses.
TL;DR: Several RNA tumour viruses contain an enzyme that synthesizes a DNA–RNA hybrid using the single stranded viral RNA as template, and hybridization experiments confirm that the DNA strand is complementary to the viral RNA.
Related Papers (5)
RNA-dependent DNA polymerase in virions of Rous sarcoma virus.
Howard M. Temin,Satoshi Mizutani +1 more