Journal ArticleDOI
Complementarity between Rous sarcoma virus (RSV) RNA and the in vitro-synthesized DNA of the virus-associated DNA polymerase.
Peter H. Duesberg,E. Canaani +1 more
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This article is published in Virology.The article was published on 1970-11-01. It has received 96 citations till now. The article focuses on the topics: Hepatitis B virus DNA polymerase & RNA-dependent RNA polymerase.read more
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Book ChapterDOI
RNA-Directed DNA Synthesis and RNA Tumor Viruses
Howard M. Temin,David Baltimore +1 more
TL;DR: It is hypothesized that the leukovirus RNA-directed DNA polymerase activity is an integral part of the ribonucleoprotein core of the virions, which suggests that the virion enzyme activity is related to normal cellular DNA polymerases, and that there are homologies between the amino acid sequences of the viral enzyme and normal cellular enzymes.
Journal ArticleDOI
Purification of the DNA Polymerase of Avian Myeloblastosis Virus
TL;DR: DNA polymerase from avian myeloblastosis virus has been purified by a combination of column chromatography and gel filtration methods and possesses the RNA-, DNA-, and hybrid-directed polymerase activities found in the virion.
Journal ArticleDOI
Infectious C-type virus isolated from a baboon placenta
Raoul E. Benveniste,Michael M. Lieber,David M. Livingston,Charles J. Sherr,George J. Todaro,Seymour S. Kalter +5 more
TL;DR: Nucleic acid hybridisation with a 3H-DNA transcript of the viral genome demonstrates that this virus is genetically different from previously studied mammalian C-type viruses, and suggests that M7 is an endogenous baboon virus.
Journal ArticleDOI
RNA metabolism of murine leukemia virus: Detection of virus-specific RNA sequences in infected and uninfected cells and identification of virus-specific messenger RNA
Hung Fan,David Baltimore +1 more
TL;DR: Virus-specific RNA was found to exist in infected cells in three major size classes: 60–70 S RNA, 35 S RNA and 20–30 S RNA; and Messenger RNA was differentiated from other virus-specific RNAs by the criterion that virus- specific messenger RNA must change in sedimentation rate following polyribosome disaggregation.
Journal ArticleDOI
In vitro synthesis of DNA complementary to rabbit reticulocyte 10S RNA.
TL;DR: The following two articles describe successful syntheses in vitro of DNA copies of various mammalian globin mRNAs, using reverse transcriptase from avian myoblastosis virus, using poly(dT) sequences at their 3′-ends.
References
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Journal ArticleDOI
Growth of Rous sarcoma virus in chick embryo cells following irradiation of host cells or free virus.
TL;DR: The ability of X-rayed cells to initiate characteristic foci of Rous sarcoma cells remained sensitive to proflavine inhibition for a longer period of time after infection than did focus formation by the unirradiated cells, suggesting that one effect of irradiation was to delay virus development.
Journal ArticleDOI
Requirements for RNA and DNA synthesis in the transformation of mouse embryo cells by murine sarcoma virus (Moloney).
Brenda M. Buck,R. Bather +1 more
TL;DR: These experiments suggest that functional host cell DNA is necessary for continued production of this RNA-containing virus and that an important and sensitive DNA synthetic event is necessary early in the virus + cell interaction for infection and cell transformation to take place.
Related Papers (5)
RNA-dependent DNA polymerase in virions of Rous sarcoma virus.
Howard M. Temin,Satoshi Mizutani +1 more