Journal ArticleDOI
Complementarity between Rous sarcoma virus (RSV) RNA and the in vitro-synthesized DNA of the virus-associated DNA polymerase.
Peter H. Duesberg,E. Canaani +1 more
About:
This article is published in Virology.The article was published on 1970-11-01. It has received 96 citations till now. The article focuses on the topics: Hepatitis B virus DNA polymerase & RNA-dependent RNA polymerase.read more
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Book ChapterDOI
Transfer RNA into RNA tumor viruses.
Larry C. Waters,Beth C. Mullin +1 more
TL;DR: The chapter discusses that the insight and technology gained from studies of primer structure and function in RNA tumor virus systems should be helpful in the study of DNA replication in other systems.
Journal ArticleDOI
Molecular Biology: Reverse Transcriptase, the DNA Polymerase of Oncogenic RNA Viruses
TL;DR: The excitement aroused by the idea that transformation of cells by RNA tumour viruses might depend on the activity of a reverse transcriptase enzyme specific to the virus has stimulated much research since the enzyme was discovered in 1970.
Journal ArticleDOI
Extent of transcription by the RNA-dependent DNA polymerase of Rous sarcoma virus.
TL;DR: The identification of RNA-dependent DNA polymerases as components of RNA tumour viruses1–6 is consistent with Temin's provirus theory, which contends that RNA tumours transform cells by integrating DNA copies of their genome into host cell chromosomes.
Journal ArticleDOI
Cell Cycle-Dependent Activation of Rous Sarcoma Virus-Infected Stationary Chicken Cells: Avian Leukosis Virus Group-Specific Antigens and Ribonucleic Acid
TL;DR: Stationary chicken embryo fibroblasts exposed to Rous sarcoma virus remained stably infected for at least 5 days, but they did not release infectious virus or become transformed until after cell division.
Journal ArticleDOI
Heterogeneity of Murine Leukemia Virus in vitro DNA; Detection of Viral DNA in Mammalian Cells
TL;DR: Kinetic analysis of the reassociation of DNA synthesized in vitro by a murine leukemia virus DNA polymerase revealed two classes of double-stranded product representative of 25 and 100 percent of viral genetic information.
References
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Journal ArticleDOI
Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of RNA Tumour Viruses
TL;DR: Two independent groups of investigators have found evidence of an enzyme in virions of RNA tumour viruses which synthesizes DNA from an RNA template, apparently the classical process of information transfer from DNA to RNA can be inverted.
Journal ArticleDOI
RNA-dependent DNA polymerase in virions of Rous sarcoma virus.
Howard M. Temin,Satoshi Mizutani +1 more
TL;DR: Viral RNA-dependent DNA Polymerase: RNA- dependent DNA polymerase in Virions of Rous Sarcoma Virus and its role in cell reprograming is studied.
Journal ArticleDOI
Formation and properties of RNA-DNA complexes*
A.P. Nygaard,B.D. Hall +1 more
TL;DR: The rate of formation of complexes between T2 RNA and T2 DNA has been measured at various salt concentrations and temperatures and the resistance to RNase increased with increasing salt concentration but was not complete under any condition tested.
Journal ArticleDOI
Characterization of the products of DNA-directed DNA polymerases in oncogenic RNA viruses.
TL;DR: Several RNA tumour viruses contain an enzyme that synthesizes a DNA–RNA hybrid using the single stranded viral RNA as template, and hybridization experiments confirm that the DNA strand is complementary to the viral RNA.
Related Papers (5)
RNA-dependent DNA polymerase in virions of Rous sarcoma virus.
Howard M. Temin,Satoshi Mizutani +1 more