Journal ArticleDOI
Complementarity between Rous sarcoma virus (RSV) RNA and the in vitro-synthesized DNA of the virus-associated DNA polymerase.
Peter H. Duesberg,E. Canaani +1 more
About:
This article is published in Virology.The article was published on 1970-11-01. It has received 96 citations till now. The article focuses on the topics: Hepatitis B virus DNA polymerase & RNA-dependent RNA polymerase.read more
Citations
More filters
Journal ArticleDOI
Wild mouse RNA tumor viruses. A nongenetically transmitted virus group closely related to exogenous leukemia viruses of laboratory mouse strains.
TL;DR: The evidence indicates that exogenous mouse type-C viruses have been maintained in nature over a long period of evolution as a separate virus group, causative of tumors in mice by a mechanism solely involving their transmission as infectious agents.
Journal ArticleDOI
Molecular relatedness of mammalian RNA tumor viruses as determined by DNA hybridization.
TL;DR: Characterization of the DNA � RNA hybrids by hydroxylapatite chromatography revealed nucleotide sequence diversity among the viruses, detectable both by the amount of cross-hybridization and by the decreased thermal stability of heterologous hybrids.
Journal ArticleDOI
Base sequence differences between the RNA components of Harvey sarcoma virus.
TL;DR: The Harvey sarcoma-Moloney leukemia virus complex consists of 30 to 40S RNA subunits of two different size classes and contains sequences homologous to Moloney mouse leukemia virus and to information contained in a C-type rat virus, termed NRK virus.
Journal ArticleDOI
Synthesis of DNA Complements of Natural RNAs: A General Approach
TL;DR: The ability of one enzyme to accept a variety of oncogenic RNAs will obviate many of the logistical difficulties that arise, particularly in attempts to illuminate the etiology of human cancer.
Journal ArticleDOI
A new approach to the isolation of RNA-DNA hybrids and its application to the quantitative determination of labeled tumor virus RNA.
TL;DR: A procedure has been developed by which the hybrid formed between a labeled RNA and complementary DNA can be selectively separated from all other single and double-stranded nucleic acids and can be used for the detection of hybrids between labeledRNA and complementary DNAs too short to allow quantitation by conventional methods.
References
More filters
Journal ArticleDOI
Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of RNA Tumour Viruses
TL;DR: Two independent groups of investigators have found evidence of an enzyme in virions of RNA tumour viruses which synthesizes DNA from an RNA template, apparently the classical process of information transfer from DNA to RNA can be inverted.
Journal ArticleDOI
RNA-dependent DNA polymerase in virions of Rous sarcoma virus.
Howard M. Temin,Satoshi Mizutani +1 more
TL;DR: Viral RNA-dependent DNA Polymerase: RNA- dependent DNA polymerase in Virions of Rous Sarcoma Virus and its role in cell reprograming is studied.
Journal ArticleDOI
Formation and properties of RNA-DNA complexes*
A.P. Nygaard,B.D. Hall +1 more
TL;DR: The rate of formation of complexes between T2 RNA and T2 DNA has been measured at various salt concentrations and temperatures and the resistance to RNase increased with increasing salt concentration but was not complete under any condition tested.
Journal ArticleDOI
Characterization of the products of DNA-directed DNA polymerases in oncogenic RNA viruses.
TL;DR: Several RNA tumour viruses contain an enzyme that synthesizes a DNA–RNA hybrid using the single stranded viral RNA as template, and hybridization experiments confirm that the DNA strand is complementary to the viral RNA.
Related Papers (5)
RNA-dependent DNA polymerase in virions of Rous sarcoma virus.
Howard M. Temin,Satoshi Mizutani +1 more