Journal ArticleDOI
Composition and Variation of the Gel Electrophoretic Fractions of Plasma, Cerebrospinal Fluid and Urine
TLDR
The common electrophoretic band patterns of cerebrospinal fluid and urine in health and disease are analysed and the genetic variants and aquired shifts in disease are outlined.Abstract:
The electrophoretic distribution of the 14 plasma components of decisive influence on the normal gel electrophoretic plasma patterns are presented. The genetic variants and aquired shifts in disease are outlined with comments on blurred and displaced bands as a result of intercation phenomenon of individual proteins. The common electrophoretic band patterns of cerebrospinal fluid and urine in health and disease are analysed.read more
Citations
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Book ChapterDOI
Serum Proteins and the Dysproteinemias
TL;DR: This chapter discusses plasma or serum proteins and the dysproteinemias, where the major proteins of plasma are globular and only a few are fibrous, such as fibrinogen.
Journal ArticleDOI
The cold-insoluble globulin of human plasma: Studies of its essential structural features
TL;DR: Investigation of the essential structural features of the cold-insoluble globulin of human plasma showed that it is a glycoprotein containing all of the amino acids usually found in proteins, consistent with speculation that the smaller subunit may be a catabolic intermediate arising via release of peptide material containing the COOH-terminus of a parent chain.
Journal ArticleDOI
Measurement of IgG and Albumin Content of Cerebrospinal Fluid, and its Interpretation
Karin Ganrot,Carl-Bertil Laurell +1 more
TL;DR: The scatter diagram for these ratios in persons without disease of the nervous system is most useful as a reference when differentiating between local IgG production in the subarachnoid space and an increase in CSF protein for other reasons.
Journal ArticleDOI
Epidemiological Survey of Workers Exposed to Cadmium
TL;DR: The electrophoretic pattern of the urinary proteins suggests that the lesion is first glomerular and later becomes predominantly tubular (mixed proteinuria), and a slight but significant reduction in forced vital capacity, in forced expiratory volume in one second, and in peak expiratories flow rate was found in E3 workers.
Journal ArticleDOI
Identification of a Pharmacologically Active Metabolite of Mycophenolic Acid in Plasma of Transplant Recipients Treated with Mycophenolate Mofetil
TL;DR: It was shown that in clinical samples from heart, kidney, and liver recipients, the relative amounts of M-2 correlate with the bias between MPA values determined with HPLC and the immunoassay, and in pharmacokinetic studies, the areas under the concentration-time curve for both M-1 and M- 2 can account for∼10% of those of MPA.
References
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Journal ArticleDOI
Serum and urinary lysozyme (muramidase) in monocytic and monomyelocytic leukemia
TL;DR: Present evidence indicates that ly sozyme is the principal, if not the sole, product of the proliferating monocytes in monocytic and monomyelocytic leukemia, and quantitation of serum and urine lysozyme should be a useful diagnostic procedure for these leukemias.
Journal ArticleDOI
Differentiation of glomerular, tubular, and normal proteinuria: determinations of urinary excretion of beta-2-macroglobulin, albumin, and total protein.
TL;DR: Results suggest that quantitative determinations of urinary beta(2)-microglobulin and urinary albumin may be useful for detecting disorders of the renal handling of plasma proteins and seem to suggest a selective tubular reabsorption of the two proteins.
Journal ArticleDOI
A lipoprotein characterizing obstructive jaundice. I. Method for quantitative separation and identification of lipoproteins in jaundiced subjects
TL;DR: This study indicates that the plasma lipoprotein pattern in obstructive jaundice is characterized by a decreased concentration of HDL, an increased concentration of LDL, and the presence in the LDL fraction of varying amounts of a specific lipop protein, LP-X, immunochemically and chemically distinct from LP-A and LP-B.
Journal ArticleDOI
Genetic polymorphism of the third component of human complement (C′3)
TL;DR: Polymorphism of human C'3 has been defined by prolonged agarose electrophoresis of fresh serum and at least four, and probably five, alleles have been identified by the electrophoretic mobilities of gene products.
Journal ArticleDOI
The development of immunoglobulinlevels in man
Mathea R. Allansmith,Mathea R. Allansmith,Barbara H. McClellan,Barbara H. McClellan,M. Butterworth,M. Butterworth,J.R. Maloney,J.R. Maloney +7 more
TL;DR: The development of IgG, IgA, and IgM levels from birth, through the newborn period, infancy, childhood, and into adulthood has been studied with the use of 1,241 sera from 939 subjects.