Current knowledge of Schisandra chinensis (Turcz.) Baill. (Chinese magnolia vine) as a medicinal plant species: a review on the bioactive components, pharmacological properties, analytical and biotechnological studies
TLDR
The article presents latest available information on the chemical composition of this plant species and gives a short resume of their beneficial effects in biological systems in vitro, in animals, and in humans, thus underlining their medicinal potential.Abstract:
Schisandra chinensis Turcz. (Baill.) is a plant species whose fruits have been well known in Far Eastern medicine for a long time. However, schisandra seems to be a plant still underestimated in contemporary therapy still in the countries of East Asia. The article presents latest available information on the chemical composition of this plant species. Special attention is given to dibenzo cyclooctadiene lignans. In addition, recent studies of the biological activity of dibenzocyclooctadiene lignans and schisandra fruit extracts are recapitulated. The paper gives a short resume of their beneficial effects in biological systems in vitro, in animals, and in humans, thus underlining their medicinal potential. The cosmetic properties are depicted, too. The analytical methods used for assaying schisandra lignans in the scientific studies and also in industry are also presented. Moreover, special attention is given to the information on the latest biotechnological studies of this plant species. The intention of this review is to contribute to a better understanding of the huge potential of the pharmacological relevance of S. chinensis.read more
Citations
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Journal ArticleDOI
A review of polysaccharides from Schisandra chinensis and Schisandra sphenanthera: Properties, functions and applications
TL;DR: This review summarizes the physicochemical properties and biological functions of polysaccharides from two Schisandra fruits, and the application prospects of these bioactive macromolecules in future daily life and medicine.
Structural identification
R. Balaniuk,E. Mazer +1 more
TL;DR: It is shown that in the scope of a particular but quite general functional class it is possible to automatically choose the best equation form to represent a physical process, avoiding the hard work of analytical model definition that the designer should do.
Journal ArticleDOI
An overview of neuroprotective and cognitive enhancement properties of lignans from Schisandra chinensis
TL;DR: The experimental findings support the extracts and lignan components from S. chinensis can be used as new therapeutic agents to treat various neurodegenerative diseases and are highlighted as promising resources for the development of natural and effective agents for neuroprotective and cognitive enhancement effects.
Journal ArticleDOI
Lignans and Their Derivatives from Plants as Antivirals
TL;DR: Two types of antiviral lignan—podophyllotoxin and bicyclol, which are used to treat venereal warts and chronic hepatitis B in clinical, serve as examples of using lignans for antivirals—are discussed in some detail.
Journal ArticleDOI
Selected hepatoprotective herbal medicines: Evidence from ethnomedicinal applications, animal models, and possible mechanism of actions.
Muhammad Ali,Tariq Khan,Tariq Khan,Kaneez Fatima,Qurat ul Ain Ali,Muhammad Ovais,Ali Talha Khalil,Ikram Ullah,Abida Raza,Zabta Khan Shinwari,Muhammad Idrees,Muhammad Idrees +11 more
TL;DR: The present review focuses on the composition, pharmacology, and results of experimental trials of selected medicinal plants, finding that further research is needed to identify, characterize, and standardize the active ingredients, useful compounds, and their preparations for the treatment of liver diseases.
References
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Journal Article
Pharmacology of Schisandra chinensis Bail an overview of Russian research and uses in medicine
Alexander Panossian,G. Wikman +1 more
TL;DR: The considerable diversity of pharmacological effects of Schisandra chinensis reported in numerous studies carried out in the former USSR are described and which have been confirmed over more than 40 years of use of the plant as an official medicinal remedy.
Journal ArticleDOI
Schisandra chinensis (Turcz.) Baill
TL;DR: Different aspects of the pharmacology of Schisandra chinensis fruit and dibenzo-wx a,c cyclooctene lignans from this plant are reviewed focusing in particular on the antihepa- totoxic, antioxidant and antitumoural activities, and on the effects on physical performance and on central nervous system as discussed by the authors.
Journal ArticleDOI
The constituents of Schizandra chinensis Baill. I. Isolation and structure determination of five new lignans, gomisin A, B, C, F and G, and the absolute structure of schizandrin.
TL;DR: Five new dibenzocyclooctadiene lignans were isolated from the petroleum ether extract of fruits of Schizandra chinensis BAILL and their absolute structures were elucidated by chemical and spectral techniques.
Journal ArticleDOI
Analysis of Schisandra chinensis and Schisandra sphenanthera.
Yan Lu,Dao-Feng Chen +1 more
TL;DR: In the authors' opinion, thin-layer chromatography (TLC) is the most simple and convenient method for identification of these two crude drugs, and high-performance liquid chromatography with UV detection (HPLC-UV) isThe preferred method for quantitative analysis based on the bioactive lignans.
Journal ArticleDOI
Schisandrene, a Dibenzocyclooctadiene Lignan from Schisandra chinensis: Structure−Antioxidant Activity Relationships of Dibenzocyclooctadiene Lignans⊥
Young-Whan Choi,Satoshi Takamatsu,Shabana I. Khan,Pullela V. Srinivas,Daneel Ferreira,Jianping Zhao,Ikhlas A. Khan +6 more
TL;DR: The structure-activity relationships of the dibenzocyclooctadiene lignans showed that the exocyclic methylene functionality was essential for antioxidant activity, with the benzoyloxy group probably enhancing such effects.
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