Current knowledge of Schisandra chinensis (Turcz.) Baill. (Chinese magnolia vine) as a medicinal plant species: a review on the bioactive components, pharmacological properties, analytical and biotechnological studies
TLDR
The article presents latest available information on the chemical composition of this plant species and gives a short resume of their beneficial effects in biological systems in vitro, in animals, and in humans, thus underlining their medicinal potential.Abstract:
Schisandra chinensis Turcz. (Baill.) is a plant species whose fruits have been well known in Far Eastern medicine for a long time. However, schisandra seems to be a plant still underestimated in contemporary therapy still in the countries of East Asia. The article presents latest available information on the chemical composition of this plant species. Special attention is given to dibenzo cyclooctadiene lignans. In addition, recent studies of the biological activity of dibenzocyclooctadiene lignans and schisandra fruit extracts are recapitulated. The paper gives a short resume of their beneficial effects in biological systems in vitro, in animals, and in humans, thus underlining their medicinal potential. The cosmetic properties are depicted, too. The analytical methods used for assaying schisandra lignans in the scientific studies and also in industry are also presented. Moreover, special attention is given to the information on the latest biotechnological studies of this plant species. The intention of this review is to contribute to a better understanding of the huge potential of the pharmacological relevance of S. chinensis.read more
Citations
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A review of polysaccharides from Schisandra chinensis and Schisandra sphenanthera: Properties, functions and applications
TL;DR: This review summarizes the physicochemical properties and biological functions of polysaccharides from two Schisandra fruits, and the application prospects of these bioactive macromolecules in future daily life and medicine.
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An overview of neuroprotective and cognitive enhancement properties of lignans from Schisandra chinensis
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Lignans and Their Derivatives from Plants as Antivirals
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Selected hepatoprotective herbal medicines: Evidence from ethnomedicinal applications, animal models, and possible mechanism of actions.
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References
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Journal ArticleDOI
Dibenzo[a,c]cyclooctadiene lignans of the genus Schisandra: importance, isolation and determination.
TL;DR: In this paper, the authors used analytical methods (TLC and HPLC) for the determination of the drug fingerprint and methods for determination of constituents in drugs, mixtures and biological materials.
Journal ArticleDOI
Antitumor and immunomodulatory activity of a water-soluble low molecular weight polysaccharide from Schisandra chinensis (Turcz.) Baill.
Ting Zhao,Guanghua Mao,Mao Riwen,Ye Zou,Daheng Zheng,Weiwei Feng,Yuena Ren,Wei Wang,Zheng Wei,Jia Song,Yuanqing Chen,Liuqing Yang,Xiangyang Wu +12 more
TL;DR: The results indicated that antitumor properties of SCPP11 might be achieved by improving immune response and could be explored as a potential adjuvant against cancer used in the health food and pharmaceutical therapy.
Journal ArticleDOI
Separation and determination of lignans from seeds of Schisandra species by micellar electrokinetic capillary chromatography using ionic liquid as modifier.
TL;DR: A micellar electrokinetic chromatographic (MEKC) method using ionic liquid as modifier for the quantification of the active components of lignans found in the medicinal herbs Schisandra species was developed for the first time.
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American Herbal Pharmacopoeia : botanical pharmacognosy : microscopic characterization of botanical medicines
TL;DR: Introduction to Botanical Microscopy Pharmacognosy: From Dioscorides to Modern Herbal Medicines What's in a Name?
Journal ArticleDOI
Schisandrin B prevents doxorubicin induced cardiac dysfunction by modulation of DNA damage, oxidative stress and inflammation through inhibition of MAPK/p53 signaling.
Rajarajan Amirthalingam Thandavarayan,Vijayasree V. Giridharan,Somasundaram Arumugam,Kenji Suzuki,Kam Ming Ko,Prasanna Krishnamurthy,Kenichi Watanabe,Tetsuya Konishi +7 more
TL;DR: Sch B attenuates Dox-induced cardiotoxicity via antioxidative and anti-inflammatory effects, suggesting that Sch B protects against oxidative damage in liver, heart and brain tissues in rodents.
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