Current knowledge of Schisandra chinensis (Turcz.) Baill. (Chinese magnolia vine) as a medicinal plant species: a review on the bioactive components, pharmacological properties, analytical and biotechnological studies
TLDR
The article presents latest available information on the chemical composition of this plant species and gives a short resume of their beneficial effects in biological systems in vitro, in animals, and in humans, thus underlining their medicinal potential.Abstract:
Schisandra chinensis Turcz. (Baill.) is a plant species whose fruits have been well known in Far Eastern medicine for a long time. However, schisandra seems to be a plant still underestimated in contemporary therapy still in the countries of East Asia. The article presents latest available information on the chemical composition of this plant species. Special attention is given to dibenzo cyclooctadiene lignans. In addition, recent studies of the biological activity of dibenzocyclooctadiene lignans and schisandra fruit extracts are recapitulated. The paper gives a short resume of their beneficial effects in biological systems in vitro, in animals, and in humans, thus underlining their medicinal potential. The cosmetic properties are depicted, too. The analytical methods used for assaying schisandra lignans in the scientific studies and also in industry are also presented. Moreover, special attention is given to the information on the latest biotechnological studies of this plant species. The intention of this review is to contribute to a better understanding of the huge potential of the pharmacological relevance of S. chinensis.read more
Citations
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Phytochemical studies and biological activity of three Chinese Schisandra species (Schisandra sphenanthera, Schisandra henryi and Schisandra rubriflora): current findings and future applications
TL;DR: A review of biological studies proves that these species have a high therapeutic potential and may constitute a new East-Asian proposition for European medicine and biotechnological solutions as an alternative to plant raw materials.
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Comparative Effects of Schisandrin A, B, and C on Acne-Related Inflammation.
TL;DR: The results contribute to the understanding of the mechanisms underlying the effects of the three lignans on P. acnes-induced inflammation and suggest that schisandrins might be developed as pharmacological agents for acne therapy.
Journal ArticleDOI
Lignans from Schisandra sphenanthera protect against lithocholic acid-induced cholestasis by pregnane X receptor activation in mice.
Shicheng Fan,Conghui Liu,Yiming Jiang,Yue Gao,Yixin Chen,Kaili Fu,Xinpeng Yao,Min Huang,Huichang Bi +8 more
TL;DR: Lignans from a traditional Chinese herbal medicine, Schisandra sphenanthera, were found to significantly protect against LCA-induced intrahepatic cholestasis, as evidenced by significant decrease in liver necrosis, serum alanine aminotransferase (ALT) and alkaline phosphatase activity (ALP).
Journal ArticleDOI
Antioxidant Effects of Schisandra chinensis Fruits and Their Active Constituents
TL;DR: In this paper, the direct and indirect antioxidant effects of S. chinensis fruit extract and its bioactive compounds in the cells during normal and pathological conditions are discussed, and the authors focus on the indirect antioxidant effect.
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Herbal drugs and natural bioactive products as potential therapeutics: A review on pro-cognitives and brain boosters perspectives.
Swati Halder,Uttpal Anand,Samapika Nandy,Patrik Oleksak,Safaa Y. Qusti,Eida M. Alshammari,Gaber El-Saber Batiha,Eapen P. Koshy,Abhijit Dey +8 more
TL;DR: A review of different herbs and natural products that could act as memory enhancers and how they can be potentially utilized in the near future for the treatment of severe brain disorders is presented in this article.
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Pharmacology of Schisandra chinensis Bail.: An overview of Russian research and uses in medicine
Alexander Panossian,G. Wikman +1 more
TL;DR: Schisandra chinensis (Turcz.) Bail is often referred to as an example of a medicinal plant with use in modern Chinese medicine and has been used as an adaptogen in the official medicine of the USSR in the early 1960s.
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