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Cystinpeptide aus (S‐Acetamidomethyl‐cystein)‐peptiden durch Oxydation mit Jod: Die synthese von cyclo‐L‐cystin
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In this paper, the conversion of S-acetamidomethyl cysteine peptides to by a reaction with iodine is described, and the method is applied in the synthesis of the hitherto unknown cyclo-L-cystine.Abstract:
The conversion of S-acetamidomethyl cysteine peptides to by a reaction with iodine is described. The method is applied in the synthesis of the hitherto unknown cyclo-L-cystine. The structure of this compound was confirmed by molecular weight determination, NMR. and mass spectroscopy.read more
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Solid phase peptide synthesis utilizing 9‐fluorenylmethoxycarbonyl amino acids
Gregg B. Fields,Richard L. Noble +1 more
TL;DR: The great variety of conditions under which Fmoc solid phase peptide synthesis may be carried out represents a truly "orthogonal" scheme, and thus offers many unique opportunities for bioorganic chemistry.
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Aggregation and secondary structure of synthetic amyloid βA4 peptides of Alzheimer's disease
TL;DR: Using synthetic peptides corresponding to the natural beta A4 sequence as well as analog peptides, this model suggests that the formation of aggregates depends upon a hydrophobic effect that leads to intra- and intermolecular interactions between hydrophilic parts of the beta A 4 sequence.
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Amino Acid-Protecting Groups
TL;DR: Albert Isidro-Llobet, Mercedes Alvarez,* and Fernando Albericio* Institute for Research in Biomedicine, Barcelona Science Park, Baldiri Reixac 10, 08028 Barcelona, Spain this paper.
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Synthesis and biological activity of new quinoxaline antibiotics of echinomycin analogues.
TL;DR: The compound 1a shows remarkable cytotoxicities against human tumor various cell lines, and is active VRE (vancomycin-resistant enterococci) within MIC range 0.5-8 microg/mL.
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Unusual cardioactive peptide (CCAP) from pericardial organs of the shore crab Carcinus maenas
TL;DR: An unusual crustacean cardioactive peptide from the pericardial organs of the shore crab Carcinus maenas has been purified to homogeneity by a two-step reversed-phase HPLC procedure and confirmed by chemical synthesis of the C-terminally amidated and nonamidated forms of the peptide.
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