Journal ArticleDOI
Detection of high-grade stenoses with multislice computed tomography in heart transplant patients.
Philipp Pichler,Christian Loewe,S. Roedler,Bonni Syeda,Alfred Stadler,Arezu Aliabadi,Christoph Schukro,Florian Wolf,Andreas Zuckermann,Johannes Lammer,Heinz Sochor,Dietmar Glogar +11 more
Reads0
Chats0
TLDR
MSCT with its high specificity and high negative predictive value allows the exclusion of significant coronary artery vasculopathy in evaluable patients from the clinical point of view, this might spare additional invasive coronary angiography in heart transplant patients.Abstract:
Background Post-transplant follow-up of heart transplant patients consists of repeated coronary angiography, which is associated with high costs, discomfort and risk. We sought to determine whether multislice computed tomography (MSCT) permits the exclusion or progression of coronary artery disease in heart transplant patients. Methods MSCT scanning (Philips CT MX 8000 IDT) and invasive coronary angiography were performed on 66 consecutive heart transplant patients. One hundred milliliters of non-ionic iodinated contrast medium was applied for CT angiography. For MSCT analysis, coronary arteries and side branches with a diameter ≥1.5 mm were assessed for the presence of luminal narrowing of >70%. MSCT results were compared with those of quantitative coronary angiography analysis. Results Ten patients (17%) had one significant stenosis, whereas 3 patients (5%) had 2-vessel disease and none had 3-vessel disease. MSCT was performed successfully on 60 patients enrolled in our analysis. Forty-two of 44 patients (95%) who were estimated to be fully evaluable for MSCT were correctly classified. On per-segment–based analysis, sensitivity, specificity and positive and negative predictive values were 59%, 94%, 91% and 99.43%, respectively. After exclusion of unevaluable segments, sensitivity and specificity increased to 71% and 99.86%, respectively. On per-patient–based analysis, sensitivity, specificity and positive and negative predictive values were 88%, 97%, 88% and 97%, respectively, in evaluable transplant recipients. Conclusions MSCT with its high specificity and high negative predictive value allows the exclusion of significant coronary artery vasculopathy in evaluable patients. From the clinical point of view, this might spare additional invasive coronary angiography in heart transplant patients.read more
Citations
More filters
Journal ArticleDOI
The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients
Maria Rosa Costanzo,Anne I. Dipchand,Randall C. Starling,Allen S. Anderson,Michael Chan,Shashank Desai,Savitri Fedson,Patrick W. Fisher,Gonzalo Gonzales-Stawinski,Luigi Martinelli,David C. McGiffin,Jon Smith,David O. Taylor,Bruno Meiser,Steven A. Webber,David A. Baran,Michael P. Carboni,Thomas J. Dengler,David L. Feldman,Maria Frigerio,Abdallah G. Kfoury,Daniel Kim,Jon A. Kobashigawa,Michael A. Shullo,Josef Stehlik,Jeffrey J. Teuteberg,Patricia A. Uber,Andreas Zuckermann,Sharon A. Hunt,Michael Burch,Geetha Bhat,Charles E. Canter,Richard E. Chinnock,Marisa G. Crespo-Leiro,Reynolds M. Delgado,Fabienne Dobbels,Kathleen L. Grady,W. Kao,Jaqueline Lamour,Gareth Parry,Jignesh Patel,Daniela Pini,Jeffrey A. Towbin,Gene Wolfel,Diego H. Delgado,Howard J. Eisen,Lee R. Goldberg,Jeff Hosenpud,Maryl R. Johnson,Anne Keogh,Clive Lewis,John B. O'Connell,Joseph G. Rogers,Heather J. Ross,Stuart D. Russell,Johan Vanhaecke,Amanda W. Rowe +56 more
TL;DR: Institutional Affiliations Chair Costanzo MR: Midwest Heart Foundation, Lombard Illinois, USA Task Force 1 Dipchand A: Hospital for Sick Children, Toronto Ontario, Canada; Starling R: Cleveland Clinic Foundation, Cleveland, Ohio, USA; Starlings R: University of Chicago, Chicago, Illinois,USA; Chan M: university of Alberta, Edmonton, Alberta, Canada ; Desai S: Inova Fairfax Hospital, Fairfax, Virginia, USA.
Journal ArticleDOI
European Association of Cardiovascular Imaging/Cardiovascular Imaging Department of the Brazilian Society of Cardiology recommendations for the use of cardiac imaging to assess and follow patients after heart transplantation.
Luigi P. Badano,Marcelo Haertel Miglioranza,Thor Edvardsen,Alexandre Siciliano Colafranceschi,Denisa Muraru,Fernando Bacal,Koen Nieman,Giacomo Zoppellaro,Fabiana Goulart Marcondes Braga,Thomas Binder,Gilbert Habib,Patrizio Lancellotti +11 more
TL;DR: 3DE may be a suitable alternative to conventional 2D echocardiography to assess the size and the function of cardiac chambers and may provide a more accurate and comprehensive assessment of RV size and function.
Journal ArticleDOI
Coronary computed tomography angiography for the detection of cardiac allograft vasculopathy: a meta-analysis of prospective trials.
Omar Wever-Pinzon,Jorge Romero,Iosif Kelesidis,James Wever-Pinzon,Carlos Manrique,Deborah Budge,Stavros G. Drakos,Ileana L. Piña,Abdallah G. Kfoury,Mario J. Garcia,Josef Stehlik +10 more
TL;DR: CCTA using currently available technology is a reliable noninvasive imaging alternative to coronary angiography with an excellent sensitivity, specificity, and NPV for the detection of CAV.
Journal ArticleDOI
Detection and imaging of cardiac allograft vasculopathy.
TL;DR: This review summarizes imaging modalities that are utilized in the diagnosis and surveillance of CAV and explores newer imaging techniques that may play a future role.
Journal ArticleDOI
Korean guidelines for the appropriate use of cardiac CT.
TL;DR: The purpose of this guideline is to assist clinicians and other health professionals in the use of cardiac CT for diagnosis and treatment of heart diseases, especially in patients at high risk or suspected of heart disease.
References
More filters
Journal ArticleDOI
Detection of Coronary Artery Stenoses With Thin-Slice Multi-Detector Row Spiral Computed Tomography and Multiplanar Reconstruction
Dieter Ropers,Ulrich Baum,Karsten Pohle,Katharina Anders,Stefan Ulzheimer,Bernd Ohnesorge,Christian Schlundt,Werner Bautz,Werner G. Daniel,Stephan Achenbach +9 more
TL;DR: MDCT coronary angiography with improved spatial resolution and premedication with oral &bgr;-blockade permits detection of coronary artery stenoses with high accuracy and a low rate of unevaluable arteries.
Journal Article
Heart transplant coronary artery disease detected by coronary angiography: A multiinstitutional study of preoperative donor and recipient risk factors
Maria Rosa Costanzo,D. C. Naftel,Marc R. Pritzker,J. K. Heilman,John P. Boehmer,S. C. Brozena,G. W. Dec,Hector O. Ventura,J. K. Kirklin,Robert C. Bourge,L. W. Miller +10 more
TL;DR: Although severe angiographic allograft coronary artery disease occurs in only 7% of the patients at 5 years, its presence is highly predictive of subsequent coronary artery Disease-related events or retransplantation.
Journal ArticleDOI
Multislice spiral computed tomography coronary angiography in patients with stable angina pectoris
Nico R. Mollet,Filippo Cademartiri,Koen Nieman,Francesco Saia,Pedro A. Lemos,Eugene P. McFadden,Peter M. T. Pattynama,Patrick W. Serruys,Gabriel P. Krestin,Pim J. de Feyter +9 more
TL;DR: Sixteen-row MSCT coronary angiography permits reliable detection of significant obstructive coronary artery disease in patients with stable angina in sinus rhythm.
Journal ArticleDOI
The Registry of the International Society for Heart and Lung Transplantation: twenty-first official adult lung and heart-lung transplant report--2004.
Elbert P. Trulock,Leah B. Edwards,David O. Taylor,Mark M. Boucek,Berkeley M. Keck,Marshall I. Hertz +5 more
Journal Article
Registry of the International Society for Heart and Lung Transplantation: tenth official pediatric heart transplant report-2007
Mark M. Boucek,Paul Aurora,Leah B. Edwards,David O. Taylor,Elbert P. Trulock,Jason D. Christie,Fabienne Dobbels,Axel O. Rahmel,Berkeley M. Keck,Marshall I. Hertz +9 more
Related Papers (5)
The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients
Maria Rosa Costanzo,Anne I. Dipchand,Randall C. Starling,Allen S. Anderson,Michael Chan,Shashank Desai,Savitri Fedson,Patrick W. Fisher,Gonzalo Gonzales-Stawinski,Luigi Martinelli,David C. McGiffin,Jon Smith,David O. Taylor,Bruno Meiser,Steven A. Webber,David A. Baran,Michael P. Carboni,Thomas J. Dengler,David L. Feldman,Maria Frigerio,Abdallah G. Kfoury,Daniel Kim,Jon A. Kobashigawa,Michael A. Shullo,Josef Stehlik,Jeffrey J. Teuteberg,Patricia A. Uber,Andreas Zuckermann,Sharon A. Hunt,Michael Burch,Geetha Bhat,Charles E. Canter,Richard E. Chinnock,Marisa G. Crespo-Leiro,Reynolds M. Delgado,Fabienne Dobbels,Kathleen L. Grady,W. Kao,Jaqueline Lamour,Gareth Parry,Jignesh Patel,Daniela Pini,Jeffrey A. Towbin,Gene Wolfel,Diego H. Delgado,Howard J. Eisen,Lee R. Goldberg,Jeff Hosenpud,Maryl R. Johnson,Anne Keogh,Clive Lewis,John B. O'Connell,Joseph G. Rogers,Heather J. Ross,Stuart D. Russell,Johan Vanhaecke,Amanda W. Rowe +56 more