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Open AccessJournal ArticleDOI

Coronary computed tomography angiography for the detection of cardiac allograft vasculopathy: a meta-analysis of prospective trials.

TLDR
CCTA using currently available technology is a reliable noninvasive imaging alternative to coronary angiography with an excellent sensitivity, specificity, and NPV for the detection of CAV.
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This article is published in Journal of the American College of Cardiology.The article was published on 2014-05-20 and is currently open access. It has received 112 citations till now.

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Journal ArticleDOI

Allograft Vasculopathy: The Achilles’ Heel of Heart Transplantation

TL;DR: Treatment approaches continue to evolve, but prevention remains the focus, and newer mammalian target of rapamycin inhibitors can significantly delay the progression of CAV; however, their optimal use remains to be established.
Journal ArticleDOI

Honoring 50 Years of Clinical Heart Transplantation in Circulation: In-Depth State-of-the-Art Review.

TL;DR: The translation of heart transplantation from innovative experiments to long-term clinical success has married prescient insights with discipline and organization in the domains of surgical techniques, organ preservation, immunosuppression, organ donation and transplant logistics, infection control, and longterm graft surveillance as discussed by the authors.
Journal ArticleDOI

Interacting Mechanisms in the Pathogenesis of Cardiac Allograft Vasculopathy

TL;DR: 6 potential contributors to lesion formation are discussed, including conventional risk factors of atherosclerosis; (2) pre- or peritransplant injuries; (3) infection; (4) innate immunity; (5) T-cell-mediated immunity; and (6) B- cell- mediated immunity through production of donor-specific antibody.
References
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Journal ArticleDOI

The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews

TL;DR: In this article, an evidence-based quality assessment tool called QUADAS was proposed to assess the quality of primary studies of diagnostic accuracy, based on the results of three previously conducted reviews of the diagnostic literature.
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Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews.

TL;DR: The bivariate model can be seen as an improvement and extension of the traditional sROC approach by reanalyzing the data of a published meta-analysis of diagnostic studies reporting pairs of sensitivity and specificity.
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The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients

Maria Rosa Costanzo, +56 more
TL;DR: Institutional Affiliations Chair Costanzo MR: Midwest Heart Foundation, Lombard Illinois, USA Task Force 1 Dipchand A: Hospital for Sick Children, Toronto Ontario, Canada; Starling R: Cleveland Clinic Foundation, Cleveland, Ohio, USA; Starlings R: University of Chicago, Chicago, Illinois,USA; Chan M: university of Alberta, Edmonton, Alberta, Canada ; Desai S: Inova Fairfax Hospital, Fairfax, Virginia, USA.
Journal ArticleDOI

International Society for Heart and Lung Transplantation working formulation of a standardized nomenclature for cardiac allograft vasculopathy—2010

TL;DR: This consensus document is based on best evidence and clinical consensus derived from critical analysis of available information pertaining to angiography, intravascular ultrasound imaging, microvascular function, cardiac allograft histology, circulating immune markers, non-invasive imaging tests, and gene-based and protein-based biomarkers.
Related Papers (5)

The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients

Maria Rosa Costanzo, +56 more