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Open AccessJournal ArticleDOI

Detection of Leishmania donovani and L. tropica in Ethiopian wild rodents

TLDR
The findings suggest the eco-epidemiological importance of rodents in these foci of leishmaniasis and indicate that rodents are likely to play a role in the transmission of leishingmaniasis in Ethiopia, possibly as reservoir hosts.
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This article is published in Acta Tropica.The article was published on 2015-05-01 and is currently open access. It has received 49 citations till now. The article focuses on the topics: Leishmania tropica & Leishmania.

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Citations
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Journal ArticleDOI

Leishmaniasis: A Review on Parasite, Vector and Reservoir Host

TL;DR: This review is aimed to address briefly the parasite, the vector and the reservoir aspects in transmission of leishmaniasis in different regions of the world.
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Real-time PCR applications for diagnosis of leishmaniasis.

TL;DR: This review summarizes the qPCR-based methods in the diagnosis of leishmaniasis focusing on the recent developments and applications in this field.
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A review of visceral leishmaniasis during the conflict in South Sudan and the consequences for East African countries.

TL;DR: A strong relationship between civil unrest and VL epidemics which tend to occur among immunologically naïve migrants entering VL-endemic areas and when Leishmania-infected individuals migrate to new areas and establish additional foci of disease is found.
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Eco-epidemiology of visceral leishmaniasis in Ethiopia.

TL;DR: The available data seem incomplete to plan for a cost-effective and efficient VL control strategy, there is a need to update data on vector behaviour in specific ecosystems and the roles of domestic animals need to be ascertained, and the effectiveness and social acceptability of available vector control tools need be evaluated.
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Cutaneous Leishmaniasis Due to Leishmania aethiopica.

TL;DR: A thorough documentation of the natural evolution of L. aethiopica as well as in depth studies into the immunological and parasitological characteristics that underpin the atypical and severe clinical presentation are needed.
References
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Journal ArticleDOI

Leishmaniasis: current situation and new perspectives.

TL;DR: Research for leishmaniasis has been more and more focusing on the development of new tools such as diagnostic tests, drugs and vaccines, and the newly available control tools should allow a scaling up of control activities in priority areas.
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Visceral leishmaniasis: what are the needs for diagnosis, treatment and control?

TL;DR: Millefosine, paromomycin and liposomal amphotericin B are gradually replacing pentavalent antimonials and conventional amphoteric in B as the preferred treatments in some regions, but in other areas these drugs are still being evaluated in both mono- and combination therapies.
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PCR diagnosis and characterization of Leishmania in local and imported clinical samples.

TL;DR: The sensitivity of two PCR approaches which amplify part of the ssu rRNA gene and the ribosomal internal transcribed spacer, respectively, was determined using human and dog blood seeded with Leishmania promastigotes to diagnose leishmaniasis.
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Canine leishmaniosis - new concepts and insights on an expanding zoonosis: part one.

TL;DR: An updated view on progress in elucidating the epidemiology and pathogenesis of canine leishmaniosis is presented, and the second part focuses on advances in diagnosis, treatment and prevention.
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