Journal ArticleDOI
Direct C-F bond formation using photoredox catalysis.
Montserrat Rueda-Becerril,Olivier Mahé,Myriam Drouin,Marek B. Majewski,Julian G. West,Michael O. Wolf,Glenn M. Sammis,Jean-François Paquin +7 more
TLDR
The first example of a photoredox catalytic method for the formation of carbon-fluorine (C-F) bonds is developed, and the mild reaction conditions and use of visible light make it a practical improvement over previously developed UV-mediated decarboxylative fluorinations.Abstract:
We have developed the first example of a photoredox catalytic method for the formation of carbon–fluorine (C–F) bonds. The mechanism has been studied using transient absorption spectroscopy and involves a key single-electron transfer from the 3MLCT (triplet metal-to-ligand charge transfer) state of Ru(bpy)32+ to Selectfluor. Not only does this represent a new reaction for photoredox catalysis, but the mild reaction conditions and use of visible light also make it a practical improvement over previously developed UV-mediated decarboxylative fluorinations.read more
Citations
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Journal ArticleDOI
Organic Photoredox Catalysis
TL;DR: An overview of the basic photophysics and electron transfer theory is presented in order to provide a comprehensive guide for employing this class of catalysts in photoredox manifolds.
Journal ArticleDOI
Photoredox Catalysis in Organic Chemistry
TL;DR: This Perspective highlights the unique ability of photoredox catalysis to expedite the development of completely new reaction mechanisms, with particular emphasis placed on multicatalytic strategies that enable the construction of challenging carbon-carbon and carbon-heteroatom bonds.
Journal ArticleDOI
Monofluorination of Organic Compounds: 10 Years of Innovation.
Pier Alexandre Champagne,Justine Desroches,Jean Denys Hamel,Mathilde Vandamme,Jean-François Paquin +4 more
Journal ArticleDOI
Visible-Light-Induced Decarboxylative Functionalization of Carboxylic Acids and Their Derivatives
TL;DR: Recent advances in visible-light-induced radical decarboxylative functionalization of carboxylic acids and their derivatives are discussed herein.
Journal ArticleDOI
Photocatalysis in organic and polymer synthesis
TL;DR: This review, with over 600 references, summarizes the recent applications of photoredox catalysis for organic transformation and polymer synthesis to give an overview of this emerging field to organic and polymer chemists as well as materials scientists.
References
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Journal ArticleDOI
Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis
TL;DR: The conversion of these bench stable, benign catalysts to redox-active species upon irradiation with simple household lightbulbs represents a remarkably chemoselective trigger to induce unique and valuable catalytic processes.
Journal ArticleDOI
Fluorine in Pharmaceuticals: Looking Beyond Intuition.
TL;DR: Experimental progress in exploration of the specific influence of carbon-fluorine single bonds on docking interactions is reviewed and complementary analysis based on comprehensive searches in the Cambridge Structural Database and the Protein Data Bank is added.
Journal ArticleDOI
Ru(II) polypyridine complexes: photophysics, photochemistry, eletrochemistry, and chemiluminescence
Alberto Juris,Vincenzo Balzani,F. Barigelletti,Sebastiano Campagna,Peter Belser,A. Von Zelewsky +5 more
Journal ArticleDOI
Visible light photoredox catalysis: applications in organic synthesis
TL;DR: This tutorial review provides a historical overview of visible light photoredox catalysis in organic synthesis along with recent examples which underscore its vast potential to initiate organic transformations.
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Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis
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