Journal ArticleDOI
Early Detection of Left Atrial Strain Abnormalities by Speckle-Tracking in Hypertensive and Diabetic Patients with Normal Left Atrial Size
Sergio Mondillo,Matteo Cameli,Maria Luce Caputo,Matteo Lisi,Elisabetta Palmerini,Margherita Padeletti,Piercarlo Ballo +6 more
TLDR
In this paper, the authors explored the left atrial (LA) deformation mechanics in patients with hypertension and type 2 diabetes mellitus and normal LA size using speckle-tracking echocardiography.Abstract:
Background Systemic hypertension and type 2 diabetes mellitus are associated with impaired left atrial (LA) function, but whether LA functional abnormalities also occur in patients with hypertension and diabetes who have normal LA sizes is unknown. The aim of this study was to explore LA strain using speckle-tracking echocardiography in patients with hypertension or diabetes and normal LA size. Methods LA strain was studied by speckle-tracking echocardiography in 155 patients with hypertension or diabetes with LA volume indexes 2 (83 with hypertension, 34 with diabetes, and 38 with both diabetes and hypertension) and 36 age-matched controls. The following indexes were measured: peak atrial longitudinal strain, time to peak atrial longitudinal strain, atrial longitudinal strain during early diastole and late diastole, and peak LA strain rate during ventricular systole, early diastole, and late diastole. Results Peak atrial longitudinal strain was lower in patients with hypertension (29.0 ± 6.5%) and those with diabetes (24.7 ± 6.4%) than in controls (39.6 ± 7.8%) and further reduced in patients with diabetes and hypertension (18.3 ± 5.0%) ( P P Conclusions LA deformation mechanics are impaired in patients with hypertension or diabetes with normal LA size. The coexistence of both conditions further impairs LA performance in an additive fashion. Speckle-tracking echocardiography may be considered a promising tool for the early detection of LA strain abnormalities in these patients.read more
Citations
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Journal ArticleDOI
Normal Ranges of Left Atrial Strain by Speckle-Tracking Echocardiography: A Systematic Review and Meta-Analysis
TL;DR: The normal reference ranges for the three components of left atrial function are demonstrated and the between‐study heterogeneity is explained partly by heart rate, body surface area, and sample size.
Journal ArticleDOI
Left Atrial Structure and Function, and Left Ventricular Diastolic Dysfunction: JACC State-of-the-Art Review
TL;DR: A critical appraisal on the existing evidence for the role of LA metrics in evaluation of LVDD and consequent heart failure with preserved ejection fraction is provided.
Journal ArticleDOI
LA Strain for Categorization of LV Diastolic Dysfunction
TL;DR: LA strain measurements are feasible and allow accurate categorization of DD, because unlike the traditional parameters, it changes progressively with severity of DD.
Journal ArticleDOI
Usefulness of atrial deformation analysis to predict left atrial fibrosis and endocardial thickness in patients undergoing mitral valve operations for severe mitral regurgitation secondary to mitral valve prolapse.
Matteo Cameli,Matteo Lisi,Francesca Maria Righini,A. Massoni,Benedetta Maria Natali,Marta Focardi,Damiana Tacchini,Alessia Geyer,Valeria Curci,Cristina Di Tommaso,G Lisi,Massimo Maccherini,Mario Chiavarelli,Massimo Massetti,Piero Tanganelli,Sergio Mondillo +15 more
TL;DR: In this paper, the authors evaluated the relation between the traditional and novel atrial indexes and the extent of ultrastructural alterations, obtained from patients with severe mitral regurgitation who were undergoing surgical correction of the valvular disease.
Journal ArticleDOI
Left Atrial Mechanics: Echocardiographic Assessment and Clinical Implications
TL;DR: A critical appraisal of LA mechanics is provided, describing the fundamental concepts and methodology of LA strain and strain rate analysis, the reference values reported with different imaging techniques, and the clinical implications.
References
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Roberto M. Lang,Michelle Bierig,Richard B. Devereux,Frank A. Flachskampf,Elyse Foster,Patricia A. Pellikka,Michael H. Picard,Mary J. Roman,James B. Seward,Jack S. Shanewise,Scott D. Solomon,Kirk T. Spencer,Martin St. John Sutton,William J. Stewart +13 more
TL;DR: Members of the Chamber Quantification Writing Group are: Roberto M. Lang, MD, Fase, Michelle Bierig, MPH, RDCS, FASE, Richard B. Devereux,MD, Frank A. Flachskampf, MD and Elyse Foster, MD.
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Giuseppe Mancia,Guy De Backer,Anna F. Dominiczak,Renata Cifkova,Robert Fagard,Giuseppe Germanò,Guido Grassi,Anthony M. Heagerty,Sverre E. Kjeldsen,Stéphane Laurent,Krzysztof Narkiewicz,Luis M. Ruilope,Andrzej Rynkiewicz,Roland E. Schmieder,Harry A.J. Struijker Boudier,Alberto Zanchetti +15 more
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TL;DR: 2007 Guidelines for the Management of Arterial Hypertension : The Task Force for the management of Arterspertension of the European Society ofhypertension (ESH) and of theEuropean Society of Cardiology (ESC).
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