Effect of vitamin D supplementation during pregnancy on maternal and neonatal outcomes: a systematic review and meta-analysis of randomized controlled trials
Faustino R. Pérez-López,Vinay Pasupuleti,Edward Mezones-Holguín,Vicente A. Benites-Zapata,Priyaleela Thota,Abhishek Deshpande,Adrian V. Hernandez,Adrian V. Hernandez +7 more
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TLDR
Vitamin D supplementation during pregnancy was associated with increased circulating 25(OH)D levels, birth weight, and birth length, and was not associated with other maternal and neonatal outcomes.About:
This article is published in Fertility and Sterility.The article was published on 2015-05-01 and is currently open access. It has received 235 citations till now. The article focuses on the topics: Low birth weight & Birth weight.read more
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Journal ArticleDOI
Vitamin D supplementation for women during pregnancy
TL;DR: In this paper, the effect of supplementing with vitamin D alone or in combination with calcium or other vitamins and minerals given to women during pregnancy can safely improve maternal and neonatal outcomes.
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Maternal Mineral and Bone Metabolism During Pregnancy, Lactation, and Post-Weaning Recovery
TL;DR: This review addresses the current knowledge regarding maternal adaptations in mineral and skeletal homeostasis that occur during pregnancy, lactation, and post-weaning recovery and the impacts that these adaptations have on biochemical and hormonal parameters of mineralHomeostasis.
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Effect of vitamin D supplementation on non-skeletal disorders: a systematic review of meta-analyses and randomised trials
Philippe Autier,Patrick Mullie,Alina Macacu,Miruna Dragomir,M. Boniol,Kim Coppens,Cécile Pizot,Mathieu Boniol +7 more
TL;DR: There remains little evidence to suggest that vitamin D supplementation has an effect on most conditions, including chronic inflammation, despite use of increased doses of vitamin D, strengthening the hypothesis that low vitamin D status is a consequence of ill health, rather than its cause.
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Vitamin D and cardiovascular disease prevention
Stefan Pilz,Nicolas Verheyen,Martin R. Grübler,Martin R. Grübler,Andreas Tomaschitz,Winfried März +5 more
TL;DR: Current available evidence does not support cardiovascular benefits or harms of vitamin D supplementation with the commonly used doses, and whether vitamin D has cardiovascular effects in individuals with overt vitamin D deficiency remains to be evaluated.
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Non-skeletal health effects of vitamin D supplementation: A systematic review on findings from meta-analyses summarizing trial data.
Lars Rejnmark,Lise Sofie Bislev,Kevin D. Cashman,Gudny Eiriksdottir,Martin Gaksch,Martin R. Grübler,Martin R. Grübler,Guri Grimnes,Vilmundur Gudnason,Paul Lips,Stefan Pilz,Natasja M. van Schoor,Mairead Kiely,Rolf Jorde +13 more
TL;DR: The fact that most MAs on results from RCTs did not show a beneficial effect does not disprove the hypothesis suggested by observational findings on adverse health outcomes of low 25OHD levels.
References
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First-trimester maternal serum 25-hydroxyvitamin D3 status and pregnancy outcome
Ana M. Fernández-Alonso,Elia C. Dionis-Sánchez,Peter Chedraui,María D. González-Salmerón,Faustino R. Pérez-López +4 more
TL;DR: To determine the pregnancy outcome as a function of the first‐trimester serum 25‐hydroxyvitamin D3 [25(OH,D]D] status and to compare the 25(OH)D levels in the first and third trimesters.
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Vitamin D: The secosteroid hormone and human reproduction
TL;DR: It is advisable for pregnant and nursing women to maintain adequate levels of vitamin D, through small doses of solar exposure to facilitate natural formation of the hormone or by ingesting appropriate vitamin supplements.
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Randomized placebo-controlled trial of high-dose prenatal third-trimester vitamin D3 supplementation in Bangladesh: the AViDD trial
Daniel E Roth,Abdullah Al Mahmud,Rubhana Raqib,Evana Akhtar,Nandita Perumal,Brendon Pezzack,Abdullah H Baqui +6 more
TL;DR: Antenatal 3rd-trimester vitamin D3 supplementation (35,000 IU/week) significantly raised maternal and cord serum 25(OH)D concentrations above 50 nmol/L in almost all participants without inducing hypercalcemia or other observed safety concerns.
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High prevalence of vitamin D deficiency in Pakistani mothers and their newborns
TL;DR: To determine the prevalence of vitamin D deficiency in Pakistani parturients and their newborns and to assess the correlation between maternal and newborn serum levels of the vitamin D metabolite 25‐hydroxy vitamin D3, a study of mothers and newborns is conducted.
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Vitamin D and aging: beyond calcium and bone metabolism.
TL;DR: The evidence seems to support an association between low serum 25[OH]D levels and mortality rates (all-cause and cardiovascular) and the aging process and mortality are associated with low vitamin D levels.