Effect of vitamin D supplementation during pregnancy on maternal and neonatal outcomes: a systematic review and meta-analysis of randomized controlled trials
Faustino R. Pérez-López,Vinay Pasupuleti,Edward Mezones-Holguín,Vicente A. Benites-Zapata,Priyaleela Thota,Abhishek Deshpande,Adrian V. Hernandez,Adrian V. Hernandez +7 more
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TLDR
Vitamin D supplementation during pregnancy was associated with increased circulating 25(OH)D levels, birth weight, and birth length, and was not associated with other maternal and neonatal outcomes.About:
This article is published in Fertility and Sterility.The article was published on 2015-05-01 and is currently open access. It has received 235 citations till now. The article focuses on the topics: Low birth weight & Birth weight.read more
Citations
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Journal ArticleDOI
Vitamin D supplementation for women during pregnancy
TL;DR: In this paper, the effect of supplementing with vitamin D alone or in combination with calcium or other vitamins and minerals given to women during pregnancy can safely improve maternal and neonatal outcomes.
Journal ArticleDOI
Maternal Mineral and Bone Metabolism During Pregnancy, Lactation, and Post-Weaning Recovery
TL;DR: This review addresses the current knowledge regarding maternal adaptations in mineral and skeletal homeostasis that occur during pregnancy, lactation, and post-weaning recovery and the impacts that these adaptations have on biochemical and hormonal parameters of mineralHomeostasis.
Journal ArticleDOI
Effect of vitamin D supplementation on non-skeletal disorders: a systematic review of meta-analyses and randomised trials
Philippe Autier,Patrick Mullie,Alina Macacu,Miruna Dragomir,M. Boniol,Kim Coppens,Cécile Pizot,Mathieu Boniol +7 more
TL;DR: There remains little evidence to suggest that vitamin D supplementation has an effect on most conditions, including chronic inflammation, despite use of increased doses of vitamin D, strengthening the hypothesis that low vitamin D status is a consequence of ill health, rather than its cause.
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Vitamin D and cardiovascular disease prevention
Stefan Pilz,Nicolas Verheyen,Martin R. Grübler,Martin R. Grübler,Andreas Tomaschitz,Winfried März +5 more
TL;DR: Current available evidence does not support cardiovascular benefits or harms of vitamin D supplementation with the commonly used doses, and whether vitamin D has cardiovascular effects in individuals with overt vitamin D deficiency remains to be evaluated.
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Non-skeletal health effects of vitamin D supplementation: A systematic review on findings from meta-analyses summarizing trial data.
Lars Rejnmark,Lise Sofie Bislev,Kevin D. Cashman,Gudny Eiriksdottir,Martin Gaksch,Martin R. Grübler,Martin R. Grübler,Guri Grimnes,Vilmundur Gudnason,Paul Lips,Stefan Pilz,Natasja M. van Schoor,Mairead Kiely,Rolf Jorde +13 more
TL;DR: The fact that most MAs on results from RCTs did not show a beneficial effect does not disprove the hypothesis suggested by observational findings on adverse health outcomes of low 25OHD levels.
References
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Vitamin D status in Chinese pregnant women and their newborns in Beijing and their relationships to birth size.
Shu Jun Song,Shaoyan Si,Junli Liu,Xingming Chen,Ling Zhou,Guiyue Jia,Gen-lan Liu,Yujing Niu,Jie Wu,Wenying Zhang,Jianzhong Zhang +10 more
TL;DR: The study indicates that pregnant women and neonates residing in Beijing are at high risk of vitamin D deficiency and neonatal 25(OH)D concentrations are dependently related to maternal 25( OH)D levels.
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Maternal obesity and vitamin D sufficiency are associated with cord blood vitamin D insufficiency.
Jami L. Josefson,Joe Feinglass,Alfred Rademaker,Boyd E. Metzger,Dinah M. Zeiss,Heather E. Price,Craig B. Langman +6 more
TL;DR: Obese women transfer less 25-OH D to offspring than normal-weight women, despite similar serum levels, which underscore the evolving relationships between maternal obesity, vitamin D nutritional status, and adiposity in the neonatal period that may influence subsequent childhood and adulthood vitamin D-dependent processes.
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A nested case-control study of first-trimester maternal vitamin D status and risk for spontaneous preterm birth.
TL;DR: In a cohort of pregnant women with mostly sufficient levels of first-trimester serum 25(OH)D, vitamin D deficiency was not associated with spontaneous preterm birth.
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Vitamin D status and hypertensive disorders in pregnancy.
Heather H. Burris,Heather H. Burris,Heather H. Burris,Sheryl L. Rifas-Shiman,Susanna Y. Huh,Ken Kleinman,Augusto A. Litonjua,Emily Oken,Janet W. Rich-Edwards,Carlos A. Camargo,Matthew W. Gillman +10 more
TL;DR: Data do not support the hypothesis that higher 25(OH)D levels lower the overall risk of hypertensive disorders of pregnancy, and randomized trials of vitamin D supplementation during pregnancy should monitor for gestational hypertension.
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Effect of treatment of vitamin D deficiency and insufficiency during pregnancy on fetal growth indices and maternal weight gain: a randomized clinical trial
Sima Hashemipour,Amir Ziaee,Amir Javadi,Farideh Movahed,Khadijeh Elmizadeh,Ezzatalsadat Haji Seid Javadi,Fatemeh Lalooha +6 more
TL;DR: Multivariate regression analysis for maternal weight gain, neonatal length, Neonatal weight and neonatal head circumference showed an independent correlation with maternal vitamin D level, and treatment of low serum vitamin D during pregnancy improves fetal growth indices and maternal weightgain.