Effect of vitamin D supplementation during pregnancy on maternal and neonatal outcomes: a systematic review and meta-analysis of randomized controlled trials
Faustino R. Pérez-López,Vinay Pasupuleti,Edward Mezones-Holguín,Vicente A. Benites-Zapata,Priyaleela Thota,Abhishek Deshpande,Adrian V. Hernandez,Adrian V. Hernandez +7 more
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TLDR
Vitamin D supplementation during pregnancy was associated with increased circulating 25(OH)D levels, birth weight, and birth length, and was not associated with other maternal and neonatal outcomes.About:
This article is published in Fertility and Sterility.The article was published on 2015-05-01 and is currently open access. It has received 235 citations till now. The article focuses on the topics: Low birth weight & Birth weight.read more
Citations
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Journal ArticleDOI
Vitamin D supplementation for women during pregnancy
TL;DR: In this paper, the effect of supplementing with vitamin D alone or in combination with calcium or other vitamins and minerals given to women during pregnancy can safely improve maternal and neonatal outcomes.
Journal ArticleDOI
Maternal Mineral and Bone Metabolism During Pregnancy, Lactation, and Post-Weaning Recovery
TL;DR: This review addresses the current knowledge regarding maternal adaptations in mineral and skeletal homeostasis that occur during pregnancy, lactation, and post-weaning recovery and the impacts that these adaptations have on biochemical and hormonal parameters of mineralHomeostasis.
Journal ArticleDOI
Effect of vitamin D supplementation on non-skeletal disorders: a systematic review of meta-analyses and randomised trials
Philippe Autier,Patrick Mullie,Alina Macacu,Miruna Dragomir,M. Boniol,Kim Coppens,Cécile Pizot,Mathieu Boniol +7 more
TL;DR: There remains little evidence to suggest that vitamin D supplementation has an effect on most conditions, including chronic inflammation, despite use of increased doses of vitamin D, strengthening the hypothesis that low vitamin D status is a consequence of ill health, rather than its cause.
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Vitamin D and cardiovascular disease prevention
Stefan Pilz,Nicolas Verheyen,Martin R. Grübler,Martin R. Grübler,Andreas Tomaschitz,Winfried März +5 more
TL;DR: Current available evidence does not support cardiovascular benefits or harms of vitamin D supplementation with the commonly used doses, and whether vitamin D has cardiovascular effects in individuals with overt vitamin D deficiency remains to be evaluated.
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Non-skeletal health effects of vitamin D supplementation: A systematic review on findings from meta-analyses summarizing trial data.
Lars Rejnmark,Lise Sofie Bislev,Kevin D. Cashman,Gudny Eiriksdottir,Martin Gaksch,Martin R. Grübler,Martin R. Grübler,Guri Grimnes,Vilmundur Gudnason,Paul Lips,Stefan Pilz,Natasja M. van Schoor,Mairead Kiely,Rolf Jorde +13 more
TL;DR: The fact that most MAs on results from RCTs did not show a beneficial effect does not disprove the hypothesis suggested by observational findings on adverse health outcomes of low 25OHD levels.
References
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Expression of vitamin D-metabolizing enzymes in human adipose tissue -- the effect of obesity and diet-induced weight loss.
Louise Wamberg,Tore Christiansen,Søren K. Paulsen,Sanne Fisker,Peter Rask,Lars Rejnmark,Bjørn Richelsen,Bjørn Richelsen,Steen B. Pedersen,Steen B. Pedersen +9 more
TL;DR: AT has the capacity to metabolize VD locally, and this can be dynamically altered during obesity and weight loss, whereas the catabolic vitamin-D-24-hydroxylase CYP24A1 does not differ between lean and obese women.
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Vitamin D deficiency and supplementation during pregnancy.
TL;DR: The aim of this study is to determine the vitamin D status in pregnancy and to evaluate the effects of daily and of single‐dose vitamin D supplementation.
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Vitamin D supplementation during pregnancy: Effect on neonatal calcium homeostasis
TL;DR: The data demonstrate the importance of providing adequate maternal vitamin D stores to ensure better perinatal handling of calcium, and are of particular importance for populations at risk for hypovitaminosis D.
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Vitamin D and gestational diabetes: A systematic review and meta-analysis
TL;DR: A meta-analysis indicates a significant inverse relation of serum 25OHD and the incidence of GDM, however, it remains unclear whether this association is causal due to the observational study design of the studies.
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Assessing methods to specify the target difference for a randomised controlled trial: DELTA (Difference ELicitation in TriAls) review.
Jonathan Cook,Jenni Hislop,Temitope E Adewuyi,Kirsten Harrild,Douglas G. Altman,Craig R Ramsay,Cynthia Fraser,Brian S Buckley,Peter Fayers,Ian Harvey,Andrew Briggs,John Norrie,Dean Fergusson,Ian Ford,Luke Vale +14 more
TL;DR: A systematic review of methods for specifying a target difference in a RCT sample size calculation and production of a structured guidance document to aid the design of future trials is developed.