Journal ArticleDOI
Effects of acute and chronic ethanol administration on ribosomal protein synthesis in mouse brain and liver
Kinya Kuriyama,Kinya Kuriyama,Paul Y. Sze,Paul Y. Sze,Gregory E. Rauscher,Gregory E. Rauscher +5 more
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TLDR
Incorporation of amino acid into protein was reduced in both brain and liver ribosomes 1.5–3 hours after a single administration of ethanol, suggesting ribosomal protein synthesis is rather insensitive to the in vitro addition ofanol, as compared with the in vivo administration.About:
This article is published in Life Sciences.The article was published on 1971-02-22. It has received 86 citations till now. The article focuses on the topics: Ribosomal protein & Ribosomal RNA.read more
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Effects of ethanol on lipid metabolism.
TL;DR: The capacity of lipoprotein production and hyperlipemia development increases during chronic alcohol consumption, probably as a result of the concomitant hypertrophy of the endoplasmic reticulum and Golgi apparatus, however, this compensation is relatively inefficient in ridding the liver of fat.
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Pathogenesis of alcohol-induced accumulation of protein in the liver.
TL;DR: Both enhanced protein synthesis and defective export contribute to the ethanol-induced accumulation of liver protein, and the decrease in liver microtubules represents a possible site for impairment of protein export.
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Effect of ethanol on the amount and enzyme activities of hepatic rough and smooth microsomal membranes.
Hiromasa Ishii,Hiromasa Ishii,Jean-Gil Joly,Jean-Gil Joly,Charles S. Lieber,Charles S. Lieber +5 more
TL;DR: A reduction of dietary fat content did not influence the effect of ethanol on the hepatic endoplasmic reticulum andCatalase activity after ethanol feeding did not increase; when expressed per mg of microsomal protein, it decreased in smooth microsomes.
Journal ArticleDOI
Alcohol, protein metabolism, and liver injury.
TL;DR: Unlike regular food, alcoholic beverages contain few, if any, vitamins, minerals, protein, or other nutrients, and, therefore, the alcoholic’s intake of these nutrients may readily become insufficient.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI
Measurement of the incorporation of radioactive amino acids into protein by a filter-paper disk method
Rusty J. Mans,G.David Novelli +1 more
TL;DR: A rapid and sensitive method has been described for the measurement of amino acid incorporation in cell-free systems and has been applied to both C14- and H3-labeled proteins.
Journal Article
p-CHLOROPHENYLALANINE: A SPECIFIC DEPLETOR OF BRAIN SEROTONIN
B K Koe,A Weissman +1 more
TL;DR: The results suggest that p -chlorophenylalanine may effect 5HT depletion by inhibiting the biosynthesis of this monoamine, possibly by blocking tryptophan hydroxylation.
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