Journal ArticleDOI
Effects of anti-inflammatory drugs upon nitrate and myeloperoxidase levels in the mouse pleurisy induced by carrageenan.
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The results indicate that the degree of inhibition of the tested drugs upon the parameters studied do not match, suggesting that differences in these effects may certainly interfere with their efficacy.About:
This article is published in Peptides.The article was published on 1999-01-01. It has received 106 citations till now. The article focuses on the topics: Myeloperoxidase & Nabumetone.read more
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Anti-Inflammatory effects of low-level laser therapy (660 nm) in the early phase in carrageenan-induced pleurisy in rat.
Emerson Soldateli Boschi,Carlos Eduardo Leite,Vasyl Custódio Saciura,Eduardo Caberlon,Adroaldo Lunardelli,Shanna Bitencourt,Denizar Alberto da Silva Melo,Jarbas Rodrigues de Oliveira +7 more
TL;DR: The potential effects of LLLT on modulating the pro‐inflammatory and anti‐inflammatory mediators of acute inflammation in a rat pleurisy model is investigated.
Journal ArticleDOI
Amiodarone has anti-inflammatory and anti-oxidative properties: an experimental study in rats with carrageenan-induced paw edema.
Zekai Halici,Gunnur Ozbakis Dengiz,Fehmi Odabasoglu,Halis Suleyman,Elif Cadirci,Mesut Halici +5 more
TL;DR: The results suggest that the anti-inflammatory effect of amiodarone on carrageenan-induced acute inflammation can be attributed to its ameliorating effect on the oxidative damage.
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Evidence of anti-inflammatory effects of Passiflora edulis in an inflammation model
Ana Beatriz Pimentel Montanher,Silvana Maria Zucolotto,Eloir Paulo Schenkel,Tânia Silvia Fröde +3 more
TL;DR: Several mechanisms, including the inhibition of pro-inflammatory cytokines, enzyme, enzymes, mediators and mediators release and/or action, appear to account for Passiflora edulis's actions.
Journal ArticleDOI
Myeloperoxidase and adenosine-deaminase levels in the pleural fluid leakage induced by carrageenan in the mouse model of pleurisy.
TL;DR: The findings support the evidence that both enzymes are markers of the inflammatory process, and provide new tools for a better understanding of the immunoregulatory pathways that occur in inflammation.
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Antioxidant therapy attenuates oxidative stress in chronic cardiopathy associated with Chagas' disease.
Leonilda Banki Maçao,Danilo Wilhelm Filho,Roberto Coury Pedrosa,Aline Pereira,Patrícia Backes,M. A. Torres,Tânia Silva Fröde +6 more
TL;DR: Results clearly indicate that the antioxidant supplementation was able to counteract the progressive oxidative stress associated with the disease.
References
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Journal ArticleDOI
Ethical guidelines for investigations of experimental pain in conscious animals.
TL;DR: The Committee for Research and Ethical Issues of the International Association for the Study of Pain (IASP®) is concerned with the ethical aspects of studies producing experimental pain and any suffering it may cause in animals.
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Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity: Assessment of inflammation in rat and hamster models
TL;DR: In this paper, an assay was devised to quantitate acute intestinal inflammation based on the assessment of myeloperoxidase activity, an enzyme found in neutrophils and, in much smaller quantities, in monocytes and macrophages.
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Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain.
Karen Seibert,Yan Zhang,Kathleen M. Leahy,Scott D. Hauser,Jaime L. Masferrer,William Perkins,Len F. Lee,Peter C. Isakson +7 more
TL;DR: In an animal model of acute inflammation, a selective inhibitor of COX-2 inhibited edema at the inflammatory site and was analgesic but had no effect on PG production in the stomach and did not cause gastric toxicity.
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Hoe 140 a new potent and long acting bradykinin-antagonist: in vivo studies
K. Wirth,F.J. Hock,Udo Dr Albus,Wolfgang Linz,H.G. Alpermann,H. Anagnostopoulos,St. Henke,G. Breipohl,W. König,J. Knolle,Bernward A. Schölkens +10 more
TL;DR: Hoe 140 has been shown to be a highly potent and long acting BK antagonist in vivo in different animal species and models and makes it appropriate to investigate further the physiological and pathophysiological role of BK.
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