Journal ArticleDOI
Electroconductive polyurethane/graphene nanocomposite for biomedical applications
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TLDR
In this paper, the development and characterization of graphene-based electroconductive materials for biomedical applications, and comparison of fabrication methods of the materials to the 3D scaffold were compared.Abstract:
Developing smart biomaterials with tailor-made properties is a key factor to successful tissue regeneration. The aims of this study were 1) development and characterization of graphene (G) based electroconductive materials for biomedical applications, 2) comparison of fabrication methods of the materials to the 3D scaffold. G has superior mechanical and biochemical properties as well as conductive. Multilayer G flakes were homogeneously dispersed into the polyurethane (PU) at 0.1, 2, 5, and 10 wt% concentrations. The PU/G were fabricated as membranes using electrospinning and solvent casting. The membranes were characterized for their electrical, mechanical, physiochemical, and biological properties. The electroconductivity of the electrospun mats was significantly higher than related casting films and G acted as electrical bridges leading to the improved electroconductivity of the composites. The mechanical properties of the mats were higher than those of the films and improved by increasing G concentration up to 5 wt% and then reduced. The cellular studies using fibroblast and endothelial cells revealed the potentials of composites to support attachment, spreading and proliferation of cells. It seems likely much higher cell supporting behavior of mats is attributed due to surface topography. It is envisioned that the offered nanofibrous electroconductive PU/G composites might have a potential application in tissue engineering.read more
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MXene/chitosan nanocoating for flexible polyurethane foam towards remarkable fire hazards reductions.
Bo Lin,Anthony Chun Yin Yuen,Ao Li,Yang Zhang,Timothy Bo Yuan Chen,Bin Yu,Eric Wai Ming Lee,Shuhua Peng,Wei Yang,Wei Yang,Hongdian Lu,Qing Nian Chan,Guan Heng Yeoh,Chun H. Wang +13 more
TL;DR: The Ti3C2/chitosan coating significantly reduced the flammability and smoke releases of PUF and showed outstanding smoke suppression ability with total smoke release decreased and peak smoke production rate reduced.
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A Brief Discussion on Advances in Polyurethane Applications
Abhijit Das,Prakash A. Mahanwar +1 more
TL;DR: In this paper, the basic chemistry of polyurethane and its recent advancements in applications in fields such as medical science, automobiles, coatings, adhesives, sealants, paints, textile, marine industry, wood composites and apparels.
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Recent advances in tissue engineering scaffolds based on polyurethane and modified polyurethane
TL;DR: This review focuses on the recent advances of PU/MPU scaffolds, especially on the biomedical applications in soft and hard tissue engineering and regenerative medicine, including biodegradation, electroactivity, surface functionalisation, and incorporation of active moieties.
Journal ArticleDOI
Multilayer nanofibrous patch comprising chamomile loaded carboxyethyl chitosan/poly(vinyl alcohol) and polycaprolactone as a potential wound dressing.
TL;DR: Electrospun multilayer nanofibrous patches with a new design developed using poly(ε-caprolactone) (PCL) and chamomile loaded carboxyethyl chitosan (CECS) and polyvinyl alcohol (PVA) in which chamamile extract was used as an antioxidant/antibacterial agent demonstrated that chammile sustained-release significantly controlled by Fickian-Diffusion mechanism.
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Progress on the Fabrication and Application of Electrospun Nanofiber Composites.
TL;DR: The continued growth of composite and modified nanofiber technology reveals its versatile properties that offer alternatives for many of current industrial and domestic issues and applications.
References
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Journal ArticleDOI
Electrospun nanofibrous structure: A novel scaffold for tissue engineering
TL;DR: A novel poly(D,L-lactide-co-glycolide) (PLGA) structure with a unique architecture produced by an electrospinning process has been developed for tissue-engineering applications, which acts to support and guide cell growth.
Journal ArticleDOI
Graphene-based nanomaterials for drug delivery and tissue engineering.
TL;DR: This article presents a comprehensive review of various types and properties of graphene family nanomaterials and highlights how these properties are being exploited for drug delivery and tissue engineering applications.
Journal ArticleDOI
Origin of Enhanced Stem Cell Growth and Differentiation on Graphene and Graphene Oxide
Wong Cheng Lee,Candy Haley Yi Xuan Lim,Hui Shi,Lena A. L. Tang,Yu Wang,Chwee Teck Lim,Kian Ping Loh +6 more
TL;DR: It is reported that the strong noncovalent binding abilities of G allow it to act as a preconcentration platform for osteogenic inducers, which accelerate MSCs growing on it toward the osteogenic lineage.
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Physical Properties of Composites Near Percolation
Ce-Wen Nan,Yang Shen,Jing Ma +2 more
TL;DR: In this article, the effects of geometric factors and intrinsic properties of the fillers and the matrix on electric and dielectric properties near percolation have been discussed, and an outlook on the future possibilities and scientific challenges in the field is given.
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The influence of fiber diameter of electrospun substrates on neural stem cell differentiation and proliferation
TL;DR: C cultured rat hippocampus-derived adult NSCs on laminin-coated electrospun Polyethersulfone fiber meshes with average fiber diameters indicated fiber topography can play a vital role in regulating differentiation and proliferation of rNSCs in culture.