Proceedings ArticleDOI
Enhancement of mixing operation through new movement strategies in digital microfluidic biochips
Piyali Datta,Amartya Dutta,Riya Majumder,Arpan Chakraborty,Debasis Dhal,Rajat Kumar Pal +5 more
- pp 611-614
TLDR
In this paper, a new application area of DMFB using equilateral triangular electrodes instead of square electrodes has been proposed, considering the design issues and the fluidic constraints while performing all the modular operations.Abstract:
Microfluidic biochip is a lab-on-a-chip system that replaces conventional laboratory experiments. Digital Microfluidic Biochip (DMFB) handles liquids as discrete droplets, and offers highly reconfigurable and scalable technology. DMFB combines electronics with biology opening the new application areas of Microelectronics, Biochemistry, and Biomedical sciences. A new application area of DMFB using equilateral triangular electrodes instead of square electrodes has been proposed, considering the design issues and the fluidic constraints while performing all the modular operations. The improvement of sample-reagent mixing procedure is a key challenge issue in bioassay implementation as mixing is the most dominating operation in DMFB; hence, the Triangular DMFB (TEDMB) system leads over the existing DMFB system. In this paper, we have presented a study of TEDMB mixers and developed mixing library for TEDMB synthesis.read more
Citations
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Journal ArticleDOI
Analysis of augmented droplet transport during electrowetting over triangular coplanar electrode array
TL;DR: In this article, the performance of droplet movement over a newly designed and fabricated triangular coplanar electrode system utilizing the principle of electrowetting on dielectric (EWOD) is extensively probed and compared with results available in the literature.
Book ChapterDOI
A Generalized Technique of Automated Pin Sharing on Hexagonal Electrode Based Digital Microfluidic Biochip Along with Its Design Methodology
TL;DR: The structural and behavioural facets of the proposed hexagonal electrode digital microfluidic biochip (HDMFB) are discussed regarding its associated methodology in comparison with the existing square electrodes.
Journal ArticleDOI
Hybrid Digital-Droplet Microfluidic Chip for Applications in Droplet Digital Nucleic Acid Amplification: Design, Fabrication and Characterization
Beatriz Jorge Coelho,Joana P. Neto,Elvira Fortunato,Rodrigo Martins,Pedro V. Baptista,Rui Igreja,Hugo Águas +6 more
TL;DR: In this article , a combination of digital microfluidics (DMF) and droplet microfluidics (DrMF) on a single substrate, where DMF enables droplet mixing and further acts as a controlled liquid supplier for a high-throughput nano-liter droplet generator.
Book ChapterDOI
An Effective Comparative Study Among the Different Geometry of Electrodes in Performing the Tasks in Digital Microfluidic Biochips
TL;DR: In this paper, the structural and behavioral aspects of the architectures as mentioned earlier and throwing sight to the enhancement of two primary modular operations such as droplet routing and mixing are addressed.
References
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Journal ArticleDOI
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Journal ArticleDOI
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Book
Electrokinetically-Driven Microfluidics and Nanofluidics
Hsueh-Chia Chang,Leslie Y. Yeo +1 more
TL;DR: In this article, the authors introduce the fundamental concepts of DC nonlinear electrokinetics due to field-induced double layer polarization and double layer effects, including dielectrophoresis and electrorotation.
Journal ArticleDOI
High-level synthesis of digital microfluidic biochips
Fei Su,Krishnendu Chakrabarty +1 more
TL;DR: This work proposes a system design methodology that attempts to apply classical high-level synthesis techniques to the design of digital microfluidic biochips and develops an optimal scheduling strategy based on integer linear programming and two heuristic techniques that scale well for large problem instances.