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Journal ArticleDOI

Equilibrium swelling behavior of dilute ionic hydrogels in electrolytic solutions

Lisa Brannon-Peppas, +1 more
- 01 Aug 1991 - 
- Vol. 16, Iss: 3, pp 319-329
TLDR
In this article, the crosslinked structure of ionic hydrogels in contact with water is analyzed and the equilibrium swelling ratio or equilibrium polymer volume fraction is shown to be a function of the polymer compatibility (as determined by the χ 1 factor), polymer structural parameters and the ionic nature of the hydrogel.
About
This article is published in Journal of Controlled Release.The article was published on 1991-08-01. It has received 79 citations till now. The article focuses on the topics: Self-healing hydrogels & Swelling.

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Citations
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Journal ArticleDOI

Hydrogels in controlled release formulations: network design and mathematical modeling

TL;DR: The objective of this article is to review the fundamentals and recent advances in hydrogel network design as well as mathematical modeling approaches related to controlled molecule release from hydrogels.
Journal ArticleDOI

New challenges in biomaterials

TL;DR: Approaches for controlling the interface between tissue and biomaterials and ways in which the engineered materials may contribute to medicine are considered.
Journal ArticleDOI

Stimulus-responsive hydrogels: Theory, modern advances, and applications

TL;DR: This extensive review identifies and discusses the multitude of response modalities that have been developed, including temperature, pH, chemical, light, electro, and shear-sensitive hydrogels.
Journal ArticleDOI

Swelling behavior of acrylic acid hydrogels prepared by γ-radiation crosslinking of polyacrylic acid in aqueous solution

TL;DR: In this article, a cross-linked polyacrylic acid (PAA) hydrogel was synthesized using a two-step method and the swelling behavior of the gels was studied as a function of the concentration of PAA in aqueous solution during γ-irradiation, radiation dose and pH of the swelling medium.
Book ChapterDOI

Biomedical membranes from hydrogels and interpolymer complexes

TL;DR: This work begins with an introduction to the structural characteristics and behavior of hydrogel membranes followed by a discussion of the types of environmentally responsive behavior seen with hydrogels.
References
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Journal ArticleDOI

Statistical mechanics of cross-linked polymer networks ii. swelling

TL;DR: In this paper, the interaction of solvents with cross-linked network structures, such as occur in vulcanized rubber, is subjected to a statistical mechanical treatment based on the model and procedure presented in the preceding paper.
Journal ArticleDOI

Statistical Mechanics of Cross‐Linked Polymer Networks I. Rubberlike Elasticity

TL;DR: In this paper, a model for the structure of a cross-linked network, such as exists in a vulcanized rubber, which is amenable to statistical treatment, is proposed, and expressions for the structural entropy of the network, and for the entropy change on deformation.
Journal ArticleDOI

Bioadhesive Polymers as Platforms for Oral Controlled Drug Delivery II: Synthesis and Evaluation of Some Swelling, Water-Insoluble Bioadhesive Polymers

TL;DR: The acrylic acid polymer showed a longer GI transit time than the methacrylic acid polymer, and this in vivo GI transit result is consistent with in vitro bioadhesion test results.
Journal ArticleDOI

Equilibrium swelling behavior of pH-sensitive hydrogels

TL;DR: In this paper, the equilibrium swelling behavior of hydrogels sensitive to pH or ionic strength changes of the swelling medium was studied using new structural models which are based on the Flory-Huggins thermodynamic theory, the rubber elasticity theory, and ionic interaction deviations therefrom.
Journal ArticleDOI

Poly(vinyl alcohol) hydrogels: reinforcement of radiation-crosslinked networks by crystallization.

TL;DR: Aqueous poly(vinyl alcohol) solutions were crosslinked via electron-beam irradiation to form transparent hydrogels of varying crosslinking densities as discussed by the authors, which showed greatly improved mechanical properties (modulus, ultimate tensile strength, tear strength).