Journal ArticleDOI
Erythrocytes as model cells for biocompatibility assessment, cytotoxicity screening of xenobiotics and drug delivery
TLDR
Findings make erythrocytes highly valuable cells for in vitro biocompatibility assessment, cytotoxicity screening of a wide variety of substances as well as drug delivery.About:
This article is published in Chemico-Biological Interactions.The article was published on 2020-12-01. It has received 30 citations till now.read more
Citations
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Journal ArticleDOI
Surface loading of nanoparticles on engineered or natural erythrocytes for prolonged circulation time: strategies and applications.
TL;DR: In this article, the authors describe various methods to attach nanoparticles and drugs to the erythrocyte surface, and discuss the key factors that influence the stability and circulation properties of the delivery system in vivo.
Journal ArticleDOI
Erythrocytes: Central Actors in Multiple Scenes of Atherosclerosis
Chloé Turpin,Aurélie Catan,Olivier Meilhac,Emmanuel Bourdon,François Canonne-Hergaux,Philippe Rondeau +5 more
TL;DR: In this paper, the role of Erythrocytes in plaque iron homeostasis and their role in atherosclerotic plaque progression has been discussed, with a special focus on glycoxidative modifications of erythrocyte.
Journal ArticleDOI
Role of SLC4 and SLC26 solute carriers during oxidative stress
Alessia Remigante,Sara Spinelli,Michael Pusch,Antonio Sarikas,Rossana Morabito,Angela Marino,Silvia Dossena +6 more
TL;DR:
Journal ArticleDOI
Red Blood Cell Inspired Strategies for Drug Delivery: Emerging Concepts and New Advances
TL;DR: This review discusses emerging concepts and new advances in such RBC-inspired strategies, including native RBCs, ghost R BCs, R BC-mimetic nanoparticles, and RBC -derived extracellular vesicles, for drug delivery.
Journal ArticleDOI
A ricin-based peptide BRIP from Hordeum vulgare inhibits Mpro of SARS-CoV-2
Prakriti Kashyap,Vijayant Bhardwaj,Mahima Chauhan,Varun M. Chauhan,Asheesh Kumar,Rituraj Purohit,Arun Kumar,Saurabh Kumar +7 more
TL;DR: In this paper , an attempt was made to identify SARS-CoV-2 main protease (Mpro) inhibitory peptides from ricin domains, and the most favorable binding site on Mpro was identified by molecular docking and steered molecular dynamics simulations.
References
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Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
TL;DR: Using this method, the liped peroxide level in the liver of rats suffering from carbon tetrachloride intoxication was investigated and was in good agreement with previously reported data obtained by measuring diene content.
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Catalase in vitro
TL;DR: In this article, the catalytic activity of catalase has been investigated using ultraviolet (UV) spectrophotometry and Titrimetric methods, which is suitable for comparative studies for large series of measurements.
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Glutathione S-transferases. The first enzymatic step in mercapturic acid formation.
TL;DR: The purification of homogeneous glutathione S-transferases B and C from rat liver is described, and only transferases A and C are immunologically related.
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Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase
TL;DR: Glutathione peroxidase activity is found to be associated with a relatively stable, nondialyzable, heat-labile, intracellular component which is separable from hemoglobin, by gel filtration and ammonium sulfate precipitation.
Journal ArticleDOI
Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues
TL;DR: The use of the foregoing analytical method in the determination of total and oxidized glutathione contents of rat blood, kidney, and liver gave values in good agreement with those obtained by previous investigators.