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Evolution and the genetics of populations. Vol. 1. Genetic and biométrie foundations.
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The article was published on 1968-01-01 and is currently open access. It has received 445 citations till now.read more
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Book ChapterDOI
The adaptive landscape as a conceptual bridge between micro- and macroevolution.
TL;DR: The status of theoretical work is reviewed and the importance of models for peak movement for evolution on stationary, unchanging landscapes is emphasized, with a focus on the evolution of the landscape itself.
Journal ArticleDOI
Multiple fitness peaks and epistasis
TL;DR: The evidence that genetic interaction is a common phenomenon in natural populations is reviewed to give strong circumstantial evidence for multiple fitness peaks, although the mapping of epistatic interactions onto fitness surfaces remains incompletely explored.
Journal ArticleDOI
Biometrics, biomathematics and the morphometric synthesis☆
TL;DR: The history and principal tools of this morphometric synthesis in their biomathematical and biometrical context are reviewed and their usefulness in a study of focal neuroanatomical anomalies in schizophrenia is demonstrated.
Journal ArticleDOI
A simple genetic basis for a complex psychological trait in laboratory mice
Jonathan Flint,Robin P. Corley,John C. DeFries,David W. Fulker,Jeffrey A. Gray,Stacey Miller,Allan C. Collins +6 more
TL;DR: Emotionality in mice is defined here by covariation in activity and defecation in a novel environment and emergence into the open arms of an elevated plus maze, which may be related to human susceptibility to anxiety or neuroticism.
Journal ArticleDOI
Normally occurring environmental and behavioral influences on gene activity: From central dogma to probabilistic epigenesis.
TL;DR: A substantial body of evidence is reviewed showing that external environmental influences on gene activation are normally occurring events in a large variety of organisms, including humans, thus extending the author's model of probabilistic epigenesis.