Journal ArticleDOI
Folate-receptor-targeted delivery of doxorubicin nano-aggregates stabilized by doxorubicin-PEG-folate conjugate.
Hyuk Sang Yoo,Tae Gwan Park +1 more
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Folate-targeted doxorubicin nano-aggregates could be a potentially useful delivery system for folate-receptor-positive cancer cells, according to results in a human tumor xenograft nude mouse model.About:
This article is published in Journal of Controlled Release.The article was published on 2004-11-24. It has received 441 citations till now. The article focuses on the topics: Folate receptor & Doxorubicin.read more
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Nanomaterials for theranostics: recent advances and future challenges.
Eun Kyung Lim,Eun Kyung Lim,Taekhoon Kim,Taekhoon Kim,Soonmyung Paik,Seungjoo Haam,Yong Min Huh,Kwangyeol Lee +7 more
TL;DR: Challenges Eun-Kyung Lim,†,‡,§ Taekhoon Kim, Soonmyung Paik, Seungjoo Haam, Yong-Min Huh,*,† and Kwangyeol Lee
Journal ArticleDOI
Nanostructured materials for applications in drug delivery and tissue engineering
TL;DR: The biological functions of encapsulated drugs and cells can be dramatically enhanced by designing biomaterials with controlled organizations at the nanometer scale.
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Nanotechnology in cancer therapeutics: bioconjugated nanoparticles for drug delivery
TL;DR: The use of bioconjugated nanoparticles for the delivery and targeting of anticancer drugs and imaging contrast agents is discussed.
Journal ArticleDOI
Folate receptor‐mediated drug targeting: From therapeutics to diagnostics
TL;DR: This review will summarize the applications of folic acid as a targeting ligand and highlight the various methods being developed for delivery of therapeutic and imaging agents to FR-expressing cells.
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Functionalized Micellar Systems for Cancer Targeted Drug Delivery
TL;DR: The purpose of this review is to draw attention to the new developments of multi-functional polymer micelles for cancer therapy with special focus on tumor targeting and controlled drug release strategies.
References
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Book
Culture of Animal Cells
TL;DR: Biology of Cultured Cells, Design and Layout, and Organotypic Culture: Problems Solving.
Journal ArticleDOI
Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes
TL;DR: The PEG‐PE's activity to prolong the circulation time of liposomes is greater than that of the ganglioside GM1, awell‐described glycolipid with this activity.
Journal ArticleDOI
Block copolymer micelles as vehicles for drug delivery
TL;DR: In this article, the authors focused on the promising features of block copolymer micelles as drug vehicles mimicking the natural carrier-systems with supramolecular structures (i.e. viruses and lipoproteins).
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Polymeric micelles as new drug carriers
Glen S. Kwon,Teruo Okano +1 more
TL;DR: Mechanistically, polymeric micelles may act as drug carriers by circumventing host defenses, circulating for prolonged periods and extravasating from the vascular system, preferentially delivering drug to solid tumors.
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Doxorubicin-loaded poly(ethylene glycol)–poly(β-benzyl-l-aspartate) copolymer micelles: their pharmaceutical characteristics and biological significance
Kazunori Kataoka,Tsuyoshi Matsumoto,Masayuki Yokoyama,Teruo Okano,Yasuhisa Sakurai,Shigeto Fukushima,Kazuya Okamoto,Glen S. Kwon +7 more
TL;DR: A remarkable improvement in blood circulation of DOX was achieved by use of PEG-PBLA micelle as a carrier presumably due to the reduced reticuloendothelial system uptake of the micelles through a steric stabilization mechanism.
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Yasuhiro Matsumura,Hiroshi Maeda +1 more