Frontal Hyperconnectivity Related to Discounting and Reversal Learning in Cocaine Subjects
Jazmin Camchong,Angus W. MacDonald,Brent G. Nelson,Christopher J. Bell,Bryon A. Mueller,Sheila M. Specker,Kelvin O. Lim +6 more
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TLDR
The present study shows that participants with chronic cocaine-dependency have hyperconnectivity within an ACC network known to be involved in social processing and "mentalizing" in addition to difficulties with delay rewards and slower adaptive learning.Citations
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The Multifaceted Role of the Ventromedial Prefrontal Cortex in Emotion, Decision Making, Social Cognition, and Psychopathology.
Jaryd Hiser,Michael Koenigs +1 more
TL;DR: Meta-analytic data is presented revealing distinct subregions within the vmPFC that correspond to each of these three functions, as well as the associations between these subregion and specific psychiatric disorders (depression, posttraumatic stress disorder, addiction, social anxiety disorder, bipolar disorder, schizophrenia, and attention-deficit/hyperactivity disorder).
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Excessive discounting of delayed reinforcers as a trans-disease process contributing to addiction and other disease-related vulnerabilities: emerging evidence.
Warren K. Bickel,David P. Jarmolowicz,E. Terry Mueller,Mikhail N. Koffarnus,Kirstin M. Gatchalian +4 more
TL;DR: It is argued that delay discounting is a trans-disease process, undergirded by an imbalance between two competing neurobehavioral decision systems.
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Resting state functional connectivity in addiction: Lessons learned and a road ahead.
TL;DR: It is suggested that a better understanding of how the insula modulates the interaction between these networks is critical for elucidating both the cognitive impairments often associated with withdrawal and the performance-enhancing effects of nicotine administration.
Journal ArticleDOI
Similarities and differences between pathological gambling and substance use disorders: a focus on impulsivity and compulsivity
Robert F. Leeman,Marc N. Potenza +1 more
TL;DR: This review was conducted to compare and contrast research findings in PG and SUDs pertaining to neurocognitive tasks, brain function, and neurochemistry, with a focus on impulsivity and compulsivity.
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The behavioral- and neuro-economic process of temporal discounting: A candidate behavioral marker of addiction
TL;DR: Initial evidence supports temporal discounting as a candidate behavioral marker for addiction and suggests that it acts as a gauge of addiction severity, correlates with all stages of addiction development, and changes with effective treatment.
References
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