Fully closed-loop insulin delivery improves glucose control of inpatients with type 2 diabetes receiving hemodialysis
Lia Bally,Lia Bally,Philipp Gubler,Hood Thabit,Hood Thabit,Hood Thabit,Sara Hartnell,Yue Ruan,Yue Ruan,Malgorzata E. Wilinska,Mark L. Evans,Mark L. Evans,Mariam Semmo,Bruno Vogt,Anthony P. Coll,Anthony P. Coll,Christoph Stettler,Roman Hovorka +17 more
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TLDR
In this paper, the authors compared the efficacy of fully automated closed-loop insulin delivery vs. usual care in patients undergoing hemodialysis while in hospital and found that those patients receiving closed loop insulin delivery significantly increased the proportion of time when a continuous glucose monitor was in the target range of 5.6-10.0 mmol/l by 37.6 percent without increasing the risk of hypoglycemia.About:
This article is published in Kidney International.The article was published on 2019-09-01 and is currently open access. It has received 43 citations till now. The article focuses on the topics: Diabetes management & Artificial pancreas.read more
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Hemodialyzed type I and type II diabetic patients in the US : Characteristics, glycemic control, and survival. Commentary
TL;DR: In this paper, the authors performed a primary data analysis of glycemic control and survival on a large national ESRD database and found that the survival rates in the subsequent 12-month period ranged from 80 to 85% across different HgbA1c strata.
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Management of diabetes and hyperglycaemia in the hospital.
TL;DR: In this paper, the authors proposed several insulin protocols to manage patients with hyperglycaemia; however, meta-analyses comparing different treatment regimens have not clearly endorsed the benefits of any particular strategy.
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Continuous Glucose Monitors and Automated Insulin Dosing Systems in the Hospital Consensus Guideline
Rodolfo J. Galindo,Guillermo E. Umpierrez,Robert J. Rushakoff,Ananda Basu,Suzanne Lohnes,James H. Nichols,Elias K. Spanakis,Elias K. Spanakis,Juan Espinoza,Nadine E. Palermo,Dessa Garnett Awadjie,Leigh B. Bak,Bruce A. Buckingham,Curtiss B. Cook,Guido Freckmann,Lutz Heinemann,Roman Hovorka,Nestoras Mathioudakis,Tonya Newman,David N O'Neal,Michaela Rickert,David B. Sacks,Jane Jeffrie Seley,Amisha Wallia,Trisha Shang,Jennifer Y Zhang,Julia Han,David C. Klonoff +27 more
TL;DR: This guideline is intended to support these technologies for the management of hospitalized patients with diabetes by developing three types of recommendations for each topic, including clinical practice, research, and hospital policies for each of the five topics.
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Evolution of Diabetes Technology
TL;DR: Decision support systems within and integrated cloud environment will further simplify, unify, and improve modern routine diabetes care.
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Fully automated closed-loop glucose control compared with standard insulin therapy in adults with type 2 diabetes requiring dialysis: an open-label, randomized crossover trial.
Charlotte K. Boughton,Charlotte K. Boughton,Afroditi Tripyla,Sara Hartnell,Aideen Daly,David Herzig,Malgorzata E. Wilinska,Cecilia Czerlau,Andrew Fry,Lia Bally,Roman Hovorka +10 more
TL;DR: In this paper, the authors evaluated the safety and efficacy of fully closed-loop insulin therapy compared with standard insulin therapy in adults with type 2 diabetes requiring dialysis, and found that closedloop improved glucose control and reduced hypoglycemia.
References
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Hyperglycemia: An Independent Marker of In-Hospital Mortality in Patients with Undiagnosed Diabetes
Guillermo E. Umpierrez,Scott D. Isaacs,Niloofar Bazargan,Xiangdong You,Leonard M. Thaler,Abbas E. Kitabchi +5 more
TL;DR: In this article, the authors determined the prevalence of in-hospital hyperglycemia and determined the survival and functional outcome of patients with and without a history of diabetes in patients admitted to the Georgia Baptist Medical Center.
Journal Article
Hyperglycemia: An independent marker of in-hospital mortality in patients with undiagnosed diabetes. Authors' reply
TL;DR: It is indicated that in-hospital hyperglycemia is a common finding and represents an important marker of poor clinical outcome and mortality in patients with and without a history of diabetes.
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Nonlinear model predictive control of glucose concentration in subjects with type 1 diabetes
Roman Hovorka,Valentina Canonico,Ludovic J. Chassin,Ulrich Haueter,Massimo Massi-Benedetti,Marco Orsini Federici,Thomas R. Pieber,Helga C. Schaller,Lukas Schaupp,Thomas Vering,Malgorzata E. Wilinska +10 more
TL;DR: Adapt nonlinear model predictive control is promising for the control of glucose concentration during fasting conditions in subjects with type 1 diabetes.
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Hypoglycemia and Clinical Outcomes in Patients With Diabetes Hospitalized in the General Ward
Alexander Turchin,Michael E. Matheny,Maria Shubina,James V. Scanlon,Bonnie C. Greenwood,Merri Pendergrass +5 more
TL;DR: Whether hypoglycemia episodes are associated with higher mortality in diabetic patients hospitalized in the general ward and the number and severity of hypoglycemic episodes and inpatient mortality, length of stay (LOS), and mortality within 1 year after discharge were evaluated.
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Comparison of glycated albumin and hemoglobin A1c levels in diabetic subjects on hemodialysis
Todd P. Peacock,Zak K. Shihabi,Anthony J. Bleyer,E.L. Dolbare,Joyce R. Byers,M. A. Knovich,Jorge Calles-Escandon,Greg Russell,Barry I. Freedman +8 more
TL;DR: In diabetic hemodialysis patients, hemoglobin A(1c) levels significantly underestimate glycemic control while those of glycated albumin more accurately reflect this control.