Journal ArticleDOI
Gender and the prevalence and progression of renal disease.
Joel Neugarten,Ladan Golestaneh +1 more
Reads0
Chats0
TLDR
Selective estrogen receptor modulators, agents that mimic many of the beneficial effects of estrogen without reproducing estrogen's deleterious effects on reproductive tissue, ameliorate the course of kidney disease in animal models and in postmenopausal women.About:
This article is published in Advances in Chronic Kidney Disease.The article was published on 2013-09-01. It has received 125 citations till now. The article focuses on the topics: Kidney disease & Estrogen.read more
Citations
More filters
Journal ArticleDOI
Sex-related disparities in CKD progression
Ana C. Ricardo,Wei Yang,Daohang Sha,Lawrence J. Appel,Jing Chen,Marie Krousel-Wood,Anjella Manoharan,Susan Steigerwalt,Jackson T. Wright,Mahboob Rahman,Sylvia E. Rosas,Milda R. Saunders,Kumar Sharma,Martha L. Daviglus,James P. Lash +14 more
TL;DR: Women in this CKD cohort had lower risk of CKD progression and death compared with men, and in multivariable regression models, women had significantly lowerrisk of ESRD, 50% eGFR decline, progression to CKD stage 5, and death.
Journal ArticleDOI
Serum uromodulin-a marker of kidney function and renal parenchymal integrity.
Jürgen E. Scherberich,Rudolf Gruber,Wolfgang Andreas Nockher,Erik Ilsø Christensen,Hans Juergen Schmitt,Victor Herbst,Matthias Block,Jürgen Kaden,Wolfgang Schlumberger +8 more
TL;DR: In this paper, an ELISA to analyse uromodulin in human serum (sUmod) was developed, validated and tested for clinical applications, and sUmod revealed a disturbed intracellular location in kidney injury.
Journal ArticleDOI
Urinary MicroRNA Profiling Predicts the Development of Microalbuminuria in Patients with Type 1 Diabetes
Christos Argyropoulos,Kai Wang,Jose Enrique Bernardo,Demetrius Ellis,Trevor J. Orchard,David J. Galas,John P. Johnson +6 more
TL;DR: Weighting microRNA measurements by their number of kidney-relevant targets improved the prognostic performance of the miRNA signature, and a microRNA signature achieved high internal validity for the future development of microalbuminuria in this dataset.
Journal ArticleDOI
Sex hormones in women with kidney disease
TL;DR: Treatment with postmenopausal hormone therapy in women with end-stage kidney disease has been associated with improved quality of life, bone health and markers of cardiovascular risk, as well as an increased risk of arteriovenous access thrombosis.
Journal ArticleDOI
Sex differences in acute kidney injury requiring dialysis
TL;DR: This study is among the first reports to highlight the protective role of female gender in AKI, and concludes that male sex is associated with an increased incidence of hospital-associated AKI-D.
References
More filters
Journal ArticleDOI
Renoprotective Effect of the Angiotensin-Receptor Antagonist Irbesartan in Patients with Nephropathy Due to Type 2 Diabetes
Edmond J Lewis,Lawrence G. Hunsicker,William R. Clarke,Tomas Berl,Marc A. Pohl,Julia B. Lewis,Eberhard Ritz,Robert C. Atkins,Richard D. Rohde,Itamar Raz +9 more
TL;DR: The angiotensin-II-receptor blocker irbesartan is effective in protecting against the progression of nephropathy due to type 2 diabetes, independent of the reduction in blood pressure it causes.
Journal ArticleDOI
Effect of Gender on the Progression of Nondiabetic Renal Disease A Meta-Analysis
TL;DR: The results indicate that men with chronic renal disease of various etiologies show a more rapid decline in renal function with time than do women.
Book
Brenner and Rector's the Kidney
TL;DR: Brenner and Rector's the kidney is described as "the most complete picture of a human kidney that has ever been written".
Journal ArticleDOI
Risk Factors for Chronic Kidney Disease: A Prospective Study of 23,534 Men and Women in Washington County, Maryland
Melanie K. Haroun,Bernard G. Jaar,Sandra C. Hoffman,George W. Comstock,Michael J. Klag,Josef Coresh +5 more
TL;DR: CKD risk shows strong graded relationships to the sixth report of the Joint National Committee on Prevention, Detection Evaluation and Treatment of High BP criteria for BP, to diabetes, and to current cigarette smoking that are at least as strong in women as in men.
Journal ArticleDOI
Prevalence of Complications in IDDM by Sex and Duration: Pittsburgh Epidemiology of Diabetes Complications Study II
Trevor J. Orchard,Janice S. Dorman,Raelene E. Maser,Dorothy J. Becker,Allan L. Drash,Demetrius Ellis,Ronald E. LaPorte,Lewis H. Kuller +7 more
TL;DR: The results suggest that the natural history of IDDM complications varies considerably by sex and that the prevalence of complications (especially renal complications in males) may be higher than previously recognized.