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Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary.

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TLDR
It is recommended that spirometry is required for the clinical diagnosis of COPD to avoid misdiagnosis and to ensure proper evaluation of severity of airflow limitation.
Abstract
Chronic obstructive pulmonary disease (COPD) remains a major public health problem. It is the fourth leading cause of chronic morbidity and mortality in the United States, and is projected to rank fifth in 2020 in burden of disease worldwide, according to a study published by the World Bank/World Health Organization. Yet, COPD remains relatively unknown or ignored by the public as well as public health and government officials. In 1998, in an effort to bring more attention to COPD, its management, and its prevention, a committed group of scientists encouraged the U.S. National Heart, Lung, and Blood Institute and the World Health Organization to form the Global Initiative for Chronic Obstructive Lung Disease (GOLD). Among the important objectives of GOLD are to increase awareness of COPD and to help the millions of people who suffer from this disease and die prematurely of it or its complications. The first step in the GOLD program was to prepare a consensus report, Global Strategy for the Diagnosis, Management, and Prevention of COPD, published in 2001. The present, newly revised document follows the same format as the original consensus report, but has been updated to reflect the many publications on COPD that have appeared. GOLD national leaders, a network of international experts, have initiated investigations of the causes and prevalence of COPD in their countries, and developed innovative approaches for the dissemination and implementation of COPD management guidelines. We appreciate the enormous amount of work the GOLD national leaders have done on behalf of their patients with COPD. Despite the achievements in the 5 years since the GOLD report was originally published, considerable additional work is ahead of us if we are to control this major public health problem. The GOLD initiative will continue to bring COPD to the attention of governments, public health officials, health care workers, and the general public, but a concerted effort by all involved in health care will be necessary.

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References
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Journal ArticleDOI

Current thoughts regarding treatment of chronic obstructive pulmonary disease

TL;DR: Pulmonary rehabilitation when coupled with smoking cessation, optimization of blood gases, and medications offers the best treatment option for patients with symptomatic airflow obstruction.
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Screening, prevention and treatment of osteoporosis in patients with chronic obstructive pulmonary disease - a population-based database study

TL;DR: Madsen et al. as discussed by the authors investigated the use of dual-energy X-ray absorptiometry (DXA) to diagnose osteoporosis in COPD patients.
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Long-term effect of almitrine bismesylate in patients with hypoxemic chronic obstructive pulmonary disease.

TL;DR: It is concluded that AB causes a long-term improvement in arterial oxygenation in hypoxemic patients with COPD residing at an altitude of 1,500 m and lower doses of AB might produce the same effect on PaO2 with less adverse associated effects, and this should be tested in future studies.
Journal ArticleDOI

Evidence suggesting that oral corticosteroids increase mortality in stable chronic obstructive pulmonary disease.

TL;DR: LTOC may increase the mortality of stable severe and very severe COPD patients, according to the data of patients randomized to non-surgery treatment in the National Emphysema Treatment Trial.
Journal ArticleDOI

Theophylline concentrations in patients with acute exacerbation of COPD.

TL;DR: The authors conclude, because the prediction rule was often inaccurate, aminophylline therapy in patients with acute exacerbation of COPD should be based on direct measurement of the serum theophyllines level.
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