Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary.
Jørgen Vestbo,Suzanne S. Hurd,Alvar Agusti,Paul W. Jones,Claus Vogelmeier,Antonio Anzueto,Peter J. Barnes,Leonardo M. Fabbri,Fernando J. Martinez,Masaharu Nishimura,Robert A. Stockley,Don D. Sin,Roberto Rodriguez-Roisin +12 more
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TLDR
It is recommended that spirometry is required for the clinical diagnosis of COPD to avoid misdiagnosis and to ensure proper evaluation of severity of airflow limitation.Abstract:
Chronic obstructive pulmonary disease (COPD) remains a major public health problem. It is the fourth leading cause of chronic morbidity and mortality in the United States, and is projected to rank fifth in 2020 in burden of disease worldwide, according to a study published by the World Bank/World Health Organization. Yet, COPD remains relatively unknown or ignored by the public as well as public health and government officials. In 1998, in an effort to bring more attention to COPD, its management, and its prevention, a committed group of scientists encouraged the U.S. National Heart, Lung, and Blood Institute and the World Health Organization to form the Global Initiative for Chronic Obstructive Lung Disease (GOLD). Among the important objectives of GOLD are to increase awareness of COPD and to help the millions of people who suffer from this disease and die prematurely of it or its complications. The first step in the GOLD program was to prepare a consensus report, Global Strategy for the Diagnosis, Management, and Prevention of COPD, published in 2001. The present, newly revised document follows the same format as the original consensus report, but has been updated to reflect the many publications on COPD that have appeared. GOLD national leaders, a network of international experts, have initiated investigations of the causes and prevalence of COPD in their countries, and developed innovative approaches for the dissemination and implementation of COPD management guidelines. We appreciate the enormous amount of work the GOLD national leaders have done on behalf of their patients with COPD. Despite the achievements in the 5 years since the GOLD report was originally published, considerable additional work is ahead of us if we are to control this major public health problem. The GOLD initiative will continue to bring COPD to the attention of governments, public health officials, health care workers, and the general public, but a concerted effort by all involved in health care will be necessary.read more
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The 6-min walking distance: long-term follow up in patients with COPD
Ciro Casanova,Claudia Cote,Jose M. Marin,J.P. de Torres,Armando Aguirre-Jaime,Reina A. Mendez,L. J. Dordelly,Bartolome R. Celli +7 more
TL;DR: The 6-min walking distance test provides increasingly useful information as the severity of chronic obstructive pulmonary disease increases and the rate of decline of FEV1 was greater in patients with milder airflow obstruction and lesser in Patients with lower absolute FEV 1 values.
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CPAP and survival in moderate-to-severe obstructive sleep apnoea syndrome and hypoxaemic COPD.
M-C. L. Machado,William M. Vollmer,Sonia Maria Togeiro,Andrew Bilderback,M-V. C. Oliveira,F. S. Leitão,Fernando Queiroga,Geraldo Lorenzi-Filho,Jerry A. Krishnan +8 more
TL;DR: CPAP treatment was associated with higher survival in patients with moderate-to-severe OSAS and hypoxaemic COPD receiving LTOT and patients treated with CPAP showed a significantly lower risk of death.
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Superiority of “triple” therapy with salmeterol/fluticasone propionate and tiotropium bromide versus individual components in moderate to severe COPD
TL;DR: SFC+TIO triple therapy led to greater improvements in bronchodilation compared with TIO and SFC alone and led to patient related benefits by improving TDI and use of rescue medication.
Journal ArticleDOI
Standardizing the Analysis of Physical Activity in Patients With COPD Following a Pulmonary Rehabilitation Program
Heleen Demeyer,Chris Burtin,Chris Burtin,Hans Van Remoortel,Miek Hornikx,Daniel Langer,Marc Decramer,Rik Gosselink,Wim Janssens,Thierry Troosters +9 more
TL;DR: Changes in physical activity following pulmonary rehabilitation are best measured for 4 weekdays, including only days with at least 8 h of wearing time (during waking hours) and considering the difference in DT as a covariate in the analysis.
Journal ArticleDOI
Noninvasive ventilation in acute hypercapnic respiratory failure caused by obesity hypoventilation syndrome and chronic obstructive pulmonary disease.
Andres E. Carrillo,Miquel Ferrer,Gumersindo Gonzalez-Diaz,Antonia Lopez-Martinez,Noemi Llamas,Maravillas Alcazar,Lucia Capilla,Antoni Torres +7 more
TL;DR: Patients with OHS can be treated with NIV during an episode of AHRF with similar efficacy and better outcomes than patients with COPD, and obesity was associated with less late NIV failure and hospital readmission.
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