Journal ArticleDOI
Granatumins A-G, limonoids from the seeds of a Krishna mangrove, Xylocarpus granatum.
Min-Yi Li,Xiao-Bo Yang,Jian-Yu Pan,Gang Feng,Qiang Xiao,Jari Sinkkonen,Tirumani Satyanandamurty,Jun Wu +7 more
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TLDR
Seven new limonoids (1-7) were isolated from seeds of an Indian mangrove (Xylocarpus granatum) collected from the wetlands of Krishna estuary, Andhra Pradesh, on the basis of spectroscopic data.Abstract:
Seven new limonoids (1-7), named granatumins A-G, were isolated from seeds of an Indian mangrove (Xylocarpus granatum) collected from the wetlands of Krishna estuary, Andhra Pradesh. The known compounds khayasin T, tigloylseneganolide A, 6-deoxyswietenine, swietemahonolide, febrifugin A, gedunin, xylogranatinin, phaseic acid, (2R,3R)-3,4',5,7-tetrahydroxyflavanone, and (E)-4-hydroxycinnamic acid were also isolated. The structures were established on the basis of spectroscopic data. Granatumins A and B are mexicanolides with endo-conjugated Delta(8.30) and Delta(14.15) double bonds, and granatumins F and G are polyhydroxylated phragmalins found previously in plants of the Meliaceae. Khayasin T exhibited moderate insecticidal activity against fifth instar larvae of Brontispa longissima (Gestro) at a concentration of 20 mg/L.read more
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Marine natural products.
TL;DR: This review covers the literature published in 2014 for marine natural products, with 1116 citations referring to compounds isolated from marine microorganisms and phytoplankton, green, brown and red algae, sponges, cnidarians, bryozoans, molluscs, tunicates, echinoderms, mangroves and other intertidal plants and microorganisms.
Journal ArticleDOI
Meliaceous limonoids: chemistry and biological activities.
Qin-Gang Tan,Xiao-Dong Luo +1 more
TL;DR: This paper aims to demonstrate the efforts towards in-situ applicability of EMMARM, as to provide real-time information about concrete mechanical properties such as E-modulus and compressive strength.
Journal ArticleDOI
An overview on chemical aspects and potential health benefits of limonoids and their derivatives.
TL;DR: The aim of this review article is to discuss the recent developments on limonoids chemical aspects and biological activities with the relationship between structure and activity, supporting the new possibilities for the medicinal and/or nutraceutical use of these compounds.
Journal ArticleDOI
Limonoids from the Seeds of a Hainan Mangrove, Xylocarpus granatum
TL;DR: Ten new limonoids, hainangranatumins A-J, and 25 known compounds were isolated from seeds of a Chinese mangrove, Xylocarpus granatum, collected on Hainan Island, for the first report of X-ray crystallographic structures of 9,10-seco-mexicanolides with a flexible C2-C30-C8 linkage.
Journal ArticleDOI
Limonoids from seeds of Thai Xylocarpus moluccensis.
Warin Ravangpai,Damrong Sommit,Thapong Teerawatananond,Nuntawan Sinpranee,Tanapat Palaga,Somchai Pengpreecha,Nongnuj Muangsin,Khanitha Pudhom +7 more
TL;DR: Only 7-deacetylgedunin (7), a gedunin-type limonoid, exhibited significant inhibitory activity against nitric oxide production from activated macrophages with IC(50) value less than 10 μM, suggesting that the compound has anti-inflammatory activity.
References
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Natural products from true mangrove flora: source, chemistry and bioactivities
TL;DR: The mangrove flora is a diverse group of salt-tolerant plants growing in tropical and subtropical intertidal estuarine zones and the molecular phylogeny and chemotaxonomy of trueMangrove plants is discussed.
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Antimicrobial activity of 4-hydroxybenzoic acid and trans 4-hydroxycinnamic acid isolated and identified from rice hull
TL;DR: Two antimicrobial substances in rice hull were isolated and identified as 4-hydroxybenzoic acid and trans 4-Hydroxycinnamic acid by LC-MS, and 1H- and 13C-NMR and revealed that the two substances had different inhibition profiles against various microorganisms.
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The Chemistry of the Meliaceae and Ptaeroxylaceae of Southern and Eastern Africa and Madagascar
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Gedunin, a Novel Hsp90 Inhibitor: Semisynthesis of Derivatives and Preliminary Structure–Activity Relationships
TL;DR: In an effort to further probe the mechanism of action, 19 semisynthetic derivatives of gedunin were prepared and their antiproliferative activity against MCF-7 and SkBr3 breast cancer cells determined.
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Constituents of the seeds of Swietenia mahagoni Jacq. I. Isolation, structures, and 1H- and 13C-nuclear magnetic resonance signal assignments of new tetranortriterpenoids related to swietenine and swietenolide.
TL;DR: In this paper, the tetranortriterpenoids were isolated from the cotyledons of Swietenia mahagoni (Meliaceae) along with the known tetranORTriterpenoid.