Journal ArticleDOI
Habitat association of Klebsiella species.
TLDR
The genus Klebsiella is seemingly ubiquitous in terms of its habitat associations, but phenotypic and genotypic studies have shown that "K. pneumoniae" actually consists of at least four species, all with distinct characteristics and habitats.Abstract:
The genus Klebsiella is seemingly ubiquitous in terms of its habitat associations. Klebsiella is a common opportunistic pathogen for humans and other animals, as well as being resident or transient flora (particularly in the gastrointestinal tract). Other habitats include sewage, drinking water, soils, surface waters, industrial effluents, and vegetation. Until recently, almost all these Klebsiella have been identified as one species, ie, K. pneumoniae. However, phenotypic and genotypic studies have shown that “K. pneumoniae” actually consists of at least four species, all with distinct characteristics and habitats. General habitat associations of Klebsiella species are as follows: K. pneumoniae—humans, animals, sewage, and polluted waters and soils; K. oxytoca—frequent association with most habitats; K. terrigena— unpolluted surface waters and soils, drinking water, and vegetation; K. planticola—sewage, polluted surface waters, soils, and vegetation; and K. ozaenae/K. rhinoscleromatis—infrequently detected (primarily with humans).read more
Citations
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Journal ArticleDOI
Carbapenemases in Klebsiella pneumoniae and Other Enterobacteriaceae: an Evolving Crisis of Global Dimensions
Leonidas S. Tzouvelekis,Antonios Markogiannakis,Mina Psichogiou,Panayotis T. Tassios,George L. Daikos +4 more
TL;DR: Therapeutic options for treating carbapenemase-producing enterobacteria (CPE) infect mainly hospitalized patients but also have been spreading in long-term care facilities, and pharmacodynamic simulations and experimental infections indicate that modification of the current patterns of carbapENem use against CPE warrants further attention.
Journal ArticleDOI
Klebsiella pneumoniae: Going on the Offense with a Strong Defense
Michelle K. Paczosa,Joan Mecsas +1 more
TL;DR: Recent studies have identified additional K. pneumoniae virulence factors and led to more insights about factors important for the growth of this pathogen at a variety of tissue sites, but much work is left to be done in characterizing these newly discovered factors.
Journal ArticleDOI
Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health
Kathryn E. Holt,Heiman F. L. Wertheim,Ruth N. Zadoks,Stephen Baker,Chris A. Whitehouse,David A. B. Dance,Adam Jenney,Thomas R. Connor,Li Yang Hsu,Juliëtte A. Severin,Sylvain Brisse,Hanwei Cao,Jonathan J. Wilksch,Claire L. Gorrie,Mark B. Schultz,David J. Edwards,Kinh Van Nguyen,Trung Vu Nguyen,Trinh Tuyet Dao,Martijn Mensink,Vien Le Minh,Nguyen Thi Khanh Nhu,Constance Schultsz,Kuntaman Kuntaman,Paul N. Newton,Paul N. Newton,Catrin E. Moore,Catrin E. Moore,Richard A. Strugnell,Nicholas R. Thomson,Nicholas R. Thomson +30 more
TL;DR: The DNA sequence of K. pneumoniae isolates from around the world is determined and it is shown that there is a wide spectrum of diversity, including variation within shared sequences and gain and loss of whole genes, and there is an unrecognized association between the possession of specific gene profiles associated with virulence and antibiotic resistance.
Journal ArticleDOI
Colonization, Infection, and the Accessory Genome of Klebsiella pneumoniae
TL;DR: This review will explore the associations between colonization and infection with opportunistic, antibiotic-resistant, and hypervirulent K. pneumoniae strains and the role of the accessory genome in distinguishing these groups and related species.
Journal ArticleDOI
Hypervirulent Klebsiella pneumoniae
TL;DR: Recently, several biomarkers and quantitative siderophore production have been shown to accurately predict hvKp strains, which could lead to the development of a diagnostic test for use by clinical laboratories for optimal patient care and for use in epidemiologic surveillance and research studies.
References
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Journal ArticleDOI
Bergey's Manual of Determinative Bacteriology.
Book
Manual for the identification of medical bacteria.
S. T. Cowan,K. J. Steel +1 more
TL;DR: Manual for the identification of medical bacteria as discussed by the authors, Manual for identification of Medical bacteria, مرکز فناوری اطلاعات و اشعران رسانی
Journal Article
Manual For The Identification Of Medical Bacteria
TL;DR: A manual for the identification of medical bacteria is presented for the first time in a systematic fashion.
BookDOI
Cowan and Steel's manual for the identification of medical bacteria
TL;DR: In this paper, a taxonomy of Gram-positive and Gram-negative bacteria is presented. But this taxonomy is not a complete taxonomy, and it does not cover all aspects of bacterial identification.
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Klebsiella pneumoniae: Going on the Offense with a Strong Defense
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