Hand and Wrist Involvement in Systemic Sclerosis: US Features
Véronique Freire,R Bazeli,Muriel Elhai,Raphaël Campagna,Eric Pessis,Jérôme Avouac,Yannick Allanore,Jean-Luc Drapé,Henri Guerini +8 more
TLDR
US can be used to assess features of SSc, including synovitis, tenosynvitis, calcinosis, acroosteolysis, and distal vascularization and is sensitive for calcinotic detection and acrosteolytic detection.Abstract:
We describe a layered appearance of tenosynovitis on US images in patients with systemic sclerosis; we also found a high sensitivity of US for calcinosis and acroosteolysis detection and note that the majority of patients with acroosteolysis exhibit power Doppler US signal adjacent to it.read more
Citations
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Journal ArticleDOI
Calcinosis: pathophysiology and management
Antonia Valenzuela,Lorinda Chung +1 more
TL;DR: This review identified observational studies that describe the frequency of calcinosis in SSc and associated clinical features, genetic studies in animal models of heritable disorders leading to calcium deposition, and case series and case reports describing new diagnostic approaches and therapeutic interventions.
Journal ArticleDOI
Calcinosis in scleroderma.
TL;DR: There is evidence supporting local trauma, chronic inflammation, vascular hypoxia, and dysregulation of bone matrix proteins as potential mechanisms for calcinosis cutis, and several pharmacologic therapies have been tried.
Journal ArticleDOI
Musculoskeletal involvement in systemic sclerosis
TL;DR: The most important articular, tendon, and muscular manifestations (myalgia, muscle weakness, myositis) should be carefully evaluated during the assessment of SSc patients, because these are not only common, but substantially influence the quality of life and some of them also have predictive value concerning disease activity and severity.
Journal ArticleDOI
Detection of severe digital vasculopathy in systemic sclerosis by colour Doppler sonography is associated with digital ulcers
S. Lüders,S. Friedrich,Sarah Ohrndorf,Anne-Marie Glimm,Gerd-Rüdiger Burmester,Gabriela Riemekasten,Marina Backhaus +6 more
TL;DR: CDUS of hand and finger arteries allows measurement of the extent of SSc vasculopathy, which is associated with clinical signs of chronic malperfusion, and could complement vascular diagnostics in SSc.
Journal ArticleDOI
Ultrasound characterization of cutaneous ulcers in systemic sclerosis
Yossra A. Suliman,Suzanne Kafaja,John FitzGerald,Ximena Wortsman,Jonathan Grotts,Marco Matucci-Cerrinic,Veena K. Ranganath,Daniel E. Furst,Daniel E. Furst +8 more
TL;DR: This is the first study to show the promising role of US in defining skin ulcers of SSc patients, and may support the assessment of morphology and extent of skin ulcer in SSc and can be a helpful tool for detecting underlying pathology.
References
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Richard J. Wakefield,Peter V. Balint,Marcin Szkudlarek,Emilio Filippucci,Marina Backhaus,Maria Antonietta D'Agostino,Esperanza Naredo Sanchez,Annamaria Iagnocco,Wolfgang A. Schmidt,George A W Bruyn,David Kane,Philip O'Connor,Bernhard Manger,Fred Joshua,Juhani M. Koski,Walter Grassi,Marissa Lassere,Nanno Swen,Franz Kainberger,Andrea Klauser,Mikkel Østergaard,Andrew K. Brown,Klaus P Machold,Philip G. Conaghan +23 more
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Guidelines for musculoskeletal ultrasound in rheumatology
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