Journal ArticleDOI
Hepatoprotective effect of plant polysaccharides from natural resources: A review of the mechanisms and structure-activity relationship.
TLDR
A comprehensive review of research into plant polysaccharides during recent five years was performed to provide a comprehensive perspective for better understanding the mechanism and development of poly Saccharides against liver injury.About:
This article is published in International Journal of Biological Macromolecules.The article was published on 2020-10-15. It has received 67 citations till now. The article focuses on the topics: Liver function.read more
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Chemical structure and anti-inflammatory activity of a branched polysaccharide isolated from Phellinus baumii.
TL;DR: In this paper, a 46-kDa heteropolysaccharide SHPS-1 was isolated from the fruiting bodies of Phellinus baumii, which consisted of arabinose, mannose, glucose, and galactose at a molar ratio of 2.2:15.7
Journal ArticleDOI
Structure analysis and antioxidant activity of polysaccharide-iron (III) from Cordyceps militaris mycelia.
Xiaoling Zhang,Xiaojing Zhang,Shuangshuang Gu,Li-Chao Pan,Hui-Qing Sun,Enlin Gong,Zhen-Yuan Zhu,Ting-Chi Wen,Ghoson M. Daba,Waill A. Elkhateeb +9 more
TL;DR: In this paper, the authors provided a new way for the preparation of polysaccharide-iron(III) from Cordyceps militaris, which was extracted by water extraction and alcohol precipitation.
Journal ArticleDOI
Recent advances in polysaccharides from edible and medicinal Polygonati rhizoma: From bench to market
Yanan He,Zhejie Chen,Xin Nie,Di Wang,Qi Zhang,Teng Peng,Chen Zhang,Ding-Tao Wu,Jinming Zhang +8 more
TL;DR: In this paper , the authors systematically summarize recent advances in the extraction, purification, structural characteristics, biological activities, and commercial products of polygonati rhizome polysaccharides.
Journal ArticleDOI
Structural characterization of two Hericium erinaceus polysaccharides and their protective effects on the alcohol-induced gastric mucosal injury
TL;DR: In this paper , the structural properties of two polysaccharides from Hericium erinaceus, mycelium poly-saccharide (HMP) and fruiting body poly-schemas (HFP) were investigated by spectral approaches, which showed that the distribution of HMP was more uniform compared to HFP.
Journal ArticleDOI
Recent Advancements in Microbial Polysaccharides: Synthesis and Applications
TL;DR: In this paper, the authors focused on the synthesis and potential applications of microbial polysaccharides, and the utilization of molecular biology tools to modify the structure of polysacchides has been covered.
References
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THE NF-κB AND IκB PROTEINS: New Discoveries and Insights
TL;DR: The transcription factor NF-κB has attracted widespread attention among researchers in many fields based on its unusual and rapid regulation, the wide range of genes that it controls, its central role in immunological processes, the complexity of its subunits, and its apparent involvement in several diseases.
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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
Lawrence A. Donehower,Michele Harvey,Betty L. Slagle,Mark J. McArthur,Charles A. Montgomery,Janet S. Butel,Allan Bradley +6 more
TL;DR: Observations indicate that a normal p53 gene is dispensable for embryonic development, that its absence predisposes the animal to neoplastic disease, and that an oncogenic mutant form of p53 is not obligatory for the genesis of many types of tumours.
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STATs in cancer inflammation and immunity: a leading role for STAT3
TL;DR: Signal transducer and activator of transcription proteins are central in determining whether immune responses in the tumour microenvironment promote or inhibit cancer, and STAT3 is a promising target to redirect inflammation for cancer therapy.
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A central role for JNK in obesity and insulin resistance
Jiro Hirosumi,Gurol Tuncman,Lufen Chang,Cem Z. Görgün,K. Teoman Uysal,Kazuhisa Maeda,Michael Karin,Gökhan S. Hotamisligil +7 more
TL;DR: It is shown that JNK activity is abnormally elevated in obesity and an absence of JNK1 results in decreased adiposity, significantly improved insulin sensitivity and enhanced insulin receptor signalling capacity in two different models of mouse obesity.
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The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress
TL;DR: A possible role of the Nrf2-antioxidant response element transcriptional pathway in neuroprotection and the nature of this pathway and the mechanisms by which Keap1 acts to repress NRF2 activity are the topics of discussion in this minireview.